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Background <p>Ultrasound-guided percutaneous cholecystostomy (US-PC) is widely used in high-risk surgical patients with acute cholecystitis. Still, success and safety rates specific to US guidance are not always distinguished within mixed 'image-guided' series.</p> Objective <p>To estimate technical success, clinical success, and major complication rates of US-PC. Methods. Primary studies explicitly reporting US-PC or with separable data were included. Primary outcomes: technical success, clinical success (as defined by the study), and major adverse events (AEs). Single-arm meta-analysis using random-effects (logit, continuity correction); heterogeneity by I2 and prediction interval. Results. Four eligible single-arm studies for technical success (<i>N</i> = 466). Pooled technical success 99.3% (95%CI 97.8–99.8; I2 = 0%). Three studies (<i>N</i> = 223) reported clinical success: pooled 97.6% (95%CI 83.4–99.7; I<sup>2</sup>≈64% due to varying definitions). Two studies (<i>N</i> = 293) reported major AEs: pooled 1.7% (95%CI 0.7–4.1; I<sup>2</sup> = 0%). Thirty-day mortality is available from one large study (6.2%). Conclusions. In high-risk patients, US-PC demonstrates very high technical success and low major complication rates; clinical success is high but variably defined across studies. Further direct comparisons and standardized definitions are warranted.</p>

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Ultrasound-guided percutaneous cholecystostomy for acute cholecystitis: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月10日

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  • Andrea Boccatonda,
  • Alice Brighenti,
  • Marco Musmeci,
  • Nicola Venturoli,
  • Livia Masi,
  • Daniela Agostinelli,
  • Sofia Maria Bakken,
  • Susanna Vicari,
  • Cosima Schiavone,
  • Carla Serra

摘要

Background

Ultrasound-guided percutaneous cholecystostomy (US-PC) is widely used in high-risk surgical patients with acute cholecystitis. Still, success and safety rates specific to US guidance are not always distinguished within mixed 'image-guided' series.

Objective

To estimate technical success, clinical success, and major complication rates of US-PC. Methods. Primary studies explicitly reporting US-PC or with separable data were included. Primary outcomes: technical success, clinical success (as defined by the study), and major adverse events (AEs). Single-arm meta-analysis using random-effects (logit, continuity correction); heterogeneity by I2 and prediction interval. Results. Four eligible single-arm studies for technical success (N = 466). Pooled technical success 99.3% (95%CI 97.8–99.8; I2 = 0%). Three studies (N = 223) reported clinical success: pooled 97.6% (95%CI 83.4–99.7; I2≈64% due to varying definitions). Two studies (N = 293) reported major AEs: pooled 1.7% (95%CI 0.7–4.1; I2 = 0%). Thirty-day mortality is available from one large study (6.2%). Conclusions. In high-risk patients, US-PC demonstrates very high technical success and low major complication rates; clinical success is high but variably defined across studies. Further direct comparisons and standardized definitions are warranted.