Purpose of Review <p>Frailty describes the vulnerability and lack of adaptability to physiologic stressors imposed by aging and advanced medical diseases. This insult is augmented in chronic lung disease because of the disease, and it's imposed disabilities thus increasing morbidity and mortality. The purpose of this article is to cite that if frailty is identified to be related to lung disease in lung transplant candidates, it may be rectified thus allowing these patients to get lung transplant and have optimal outcomes.</p> Recent Findings <p>Even after years of identifying the concept of frailty, we do not have a gold standard method to quantify it in chronic lung disease. Historically, most institutions have used gerontologic models that assess physical strength, however, in recent years modifications to standard tests, addition of molecular markers, and adding cognitive function to the concepts of frailty have increased the tests’ performance in lung transplant candidates, however, further studies are needed.</p> Summary <p>In this review, we will discuss the concept of frailty in chronic lung disease and in lung transplantation to understand the distinctive features that together define frailty and the need for better quantification methods to define frailty in this population.</p>