<p>This study presents a comparative thermodynamic and environmental evaluation of two integrated cooling systems: the absorption - vapor compression refrigeration cycle with intercooling (ABS-VCRC) and a novel proposed configuration, the absorption ejector-booster refrigeration cycle with intercooling (ABS-EBRC). To the best of knowledge, this work introduces ABS-EBRC as a novel hybrid cycle that has not been previously analyzed in literature. Parametric investigations were conducted to examine the influence of condenser, evaporator, and generator temperatures on system performance. Key indicators including coefficient of performance (COP), exergetic coefficient of performance (ECOP), net work input, and total exergy destruction were systematically evaluated. The results demonstrate that ABS-EBRC consistently outperforms ABS-VCRC, achieving approximately 4–5% higher COP and ECOP, and 17–20% lower net work input under the same operating conditions. Total exergy destruction analysis further confirmed the superior thermodynamic effectiveness of the proposed system. In addition, environmental and economic assessments were carried out based on annual CO₂ emissions and their associated costs for different cooling capacities. ABS-EBRC achieved reductions of about 15–18% in both emissions and environmental costs compared with ABS-VCRC, underlining its potential contribution to sustainable refrigeration. Overall, the findings highlight ABS-EBRC as a promising novel cycle concept that combines improved thermodynamic performance with tangible environmental and enviroeconomic advantage</p>