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Background <p>Concern about radiation effects is particularly significant for cancer patients who require frequent imaging for follow-up assessments. Computed tomography (CT) is a key tool in the diagnosis and monitoring of cancer. </p> Purpose <p>To demonstrate radiation dose reduction using dual-energy CT (DECT) compared with single-energy CT (SECT) in the follow-up of cancer patients. </p> Patients and methods <p>This retrospective cohort study, conducted at the Fondazione INT IRCCS G. Pascale in Naples, Italy, evaluated the effectiveness of spectral dual-energy CT in reducing radiation doses during follow-up compared with conventional CT. 80 patients undergoing oncology follow-up for different cancers underwent both DESCT and conventional CT scans. A quantitative approach focused on the analysis of radiation dose measurements (CTDI and DLP), while qualitative assessments evaluated improvements in image quality. Statistical analysis was performed using SPSS version 27.0, with paired t-tests comparing radiation doses between the two methods to determine significant differences. </p> Results <p>DECT showed statistically significant reductions in radiation exposure: mean CTDI (SECT: 9.3 ± 1.1&#xa0;mGy vs DECT: 5.7 ± 1.0&#xa0;mGy, p &lt; 0.001), DLP (SECT: 875.3 ± 112.5&#xa0;mGy·cm vs DECT: 621.0 ± 95.7&#xa0;mGy·cm, p &lt; 0.001), ED (SECT: 12.3 ± 2.0&#xa0;mSv vs DECT: 8.0 ± 1.5&#xa0;mSv, p &lt; 0.001). SNR and CNR were also improved. No statistically significant gender-based differences were found.</p> Conclusion <p>Dual-energy spectral CT significantly reduces radiation dose compared to conventional CT, with substantial decreases in CT dose index (CTDI), dose-length product (DLP), and effective dose.</p>

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Analysis of radiation dose reduction in oncological followup cases by using dual energy CT

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月15日

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  • Carmine Picone,
  • Roberta Fusco,
  • Vincenza Granata,
  • Annamaria Porto,
  • Maria Chiara Brunese,
  • Marcello Zappia,
  • Antonella Santone,
  • Alessandro Ottaiano,
  • Raffaella Mormile,
  • Eugenio Sorgente,
  • Biagio Pecori,
  • Vincenzo Cerciello,
  • Claudio Granata,
  • Antonella Petrillo,
  • Andrea Magistrelli

摘要

Background

Concern about radiation effects is particularly significant for cancer patients who require frequent imaging for follow-up assessments. Computed tomography (CT) is a key tool in the diagnosis and monitoring of cancer.

Purpose

To demonstrate radiation dose reduction using dual-energy CT (DECT) compared with single-energy CT (SECT) in the follow-up of cancer patients.

Patients and methods

This retrospective cohort study, conducted at the Fondazione INT IRCCS G. Pascale in Naples, Italy, evaluated the effectiveness of spectral dual-energy CT in reducing radiation doses during follow-up compared with conventional CT. 80 patients undergoing oncology follow-up for different cancers underwent both DESCT and conventional CT scans. A quantitative approach focused on the analysis of radiation dose measurements (CTDI and DLP), while qualitative assessments evaluated improvements in image quality. Statistical analysis was performed using SPSS version 27.0, with paired t-tests comparing radiation doses between the two methods to determine significant differences.

Results

DECT showed statistically significant reductions in radiation exposure: mean CTDI (SECT: 9.3 ± 1.1 mGy vs DECT: 5.7 ± 1.0 mGy, p < 0.001), DLP (SECT: 875.3 ± 112.5 mGy·cm vs DECT: 621.0 ± 95.7 mGy·cm, p < 0.001), ED (SECT: 12.3 ± 2.0 mSv vs DECT: 8.0 ± 1.5 mSv, p < 0.001). SNR and CNR were also improved. No statistically significant gender-based differences were found.

Conclusion

Dual-energy spectral CT significantly reduces radiation dose compared to conventional CT, with substantial decreases in CT dose index (CTDI), dose-length product (DLP), and effective dose.