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<p>Formaldehyde (FA) is an important chemical due to its reactivity and versatility. The concentration of formaldehyde reagents is the key index of production and trade. The development of optical sensors for the detection of formaldehyde reagents has hardly been reported. This paper presents the design and principle of a novel optical sensor, naphthalimide (Nap)-FA, for formaldehyde (about 13 mol/L) detection without pretreatment. Nap-FA reveals low fluorescence in aqueous environment and wide pH range. Upon the addition of FA, the fluorescence intensity of Nap-FA increased rapidly, with a response time of less than 10 min. Nap-FA demonstrates a linear fluorescence response to FA in the wide range of 0.01–13.76 mol/L with high selectivity in the presence of common impurities and formaldehyde polymerization inhibitor. Compared to standard methods, Nap-FA can be used as a fast and reliable tool for detecting formaldehyde reagents.</p>

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A Selective Fluorescence Sensor for Pretreatment-free Detection of Practical Formaldehyde Reagents

  • 期刊论文

  • 发表日期：

    2026年3月17日

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  • Shigang Guo,
  • Haiqiao Huang,
  • Fuping Han,
  • Shaojun Wang,
  • Xin Li,
  • Wen Sun,
  • Jiangli Fan,
  • Jianjun Du,
  • Xiwen Zhang,
  • Xiaojun Peng

摘要

Formaldehyde (FA) is an important chemical due to its reactivity and versatility. The concentration of formaldehyde reagents is the key index of production and trade. The development of optical sensors for the detection of formaldehyde reagents has hardly been reported. This paper presents the design and principle of a novel optical sensor, naphthalimide (Nap)-FA, for formaldehyde (about 13 mol/L) detection without pretreatment. Nap-FA reveals low fluorescence in aqueous environment and wide pH range. Upon the addition of FA, the fluorescence intensity of Nap-FA increased rapidly, with a response time of less than 10 min. Nap-FA demonstrates a linear fluorescence response to FA in the wide range of 0.01–13.76 mol/L with high selectivity in the presence of common impurities and formaldehyde polymerization inhibitor. Compared to standard methods, Nap-FA can be used as a fast and reliable tool for detecting formaldehyde reagents.