Scholarlink

Purpose <p>Several factors are attributed to the development of gestational diabetes mellitus (GDM), but its association with the ABO blood group is still unexplored. Hence, we performed a meta-analysis to examine this association.</p> Methods <p>Relevant articles were obtained from various databases until April 5, 2025. All related data were extracted by two authors and summarized in a customized spreadsheet. Odds ratios (ORs) and 95% confidence intervals (CIs) were computed and interpreted.</p> Results <p>The pooled analysis showed homogeneity in the outcomes. Pooled ORs show that pregnant women with non-blood type O showed more significant associations than those with blood type O.</p> Conclusion <p>Overall, the present meta-analysis suggests that individuals with non-blood type O have an increased risk of developing GDM compared to those with blood type O. However, further studies stratifying populations based on insulin resistance, gut microbiota, and inflammation in association with ABO and GDM development are needed to confirm these claims.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Non-blood type O is associated with an increased likelihood of gestational diabetes development: findings from an updated meta-analysis

  • 期刊论文

  • 发表日期：

    2025年5月30日

查看全文
  • Raphael Enrique Tiongco,
  • Miljun Catacata,
  • Pia Vanessa Basilio,
  • Eliezer John Castro,
  • Benjie Clemente,
  • Raenard Emmanuel Dayrit,
  • Michelle Charina Gomez,
  • Michael John Dominguez,
  • Shamar Lo Lasta,
  • Jefferyl Kae Pandac,
  • Maria Ruth Pineda-Cortel

摘要

Purpose

Several factors are attributed to the development of gestational diabetes mellitus (GDM), but its association with the ABO blood group is still unexplored. Hence, we performed a meta-analysis to examine this association.

Methods

Relevant articles were obtained from various databases until April 5, 2025. All related data were extracted by two authors and summarized in a customized spreadsheet. Odds ratios (ORs) and 95% confidence intervals (CIs) were computed and interpreted.

Results

The pooled analysis showed homogeneity in the outcomes. Pooled ORs show that pregnant women with non-blood type O showed more significant associations than those with blood type O.

Conclusion

Overall, the present meta-analysis suggests that individuals with non-blood type O have an increased risk of developing GDM compared to those with blood type O. However, further studies stratifying populations based on insulin resistance, gut microbiota, and inflammation in association with ABO and GDM development are needed to confirm these claims.