Thermal Ablation for Low-Risk Papillary Thyroid Microcarcinoma in the Era of Active Surveillance: A Critical Narrative Review
摘要
This critical narrative review evaluates the current role of thermal ablation (TA) for low-risk papillary thyroid microcarcinoma (PTMC) within the contemporary de-escalation framework, with particular attention to its position relative to active surveillance (AS) and surgery.
Recent FindingsTA, including radiofrequency ablation, microwave ablation, and laser ablation, has emerged as a minimally invasive local treatment for carefully selected low-risk PTMC. Current evidence suggests that TA can achieve high rates of local tumor disappearance with low major complication rates when performed at expert centers. However, most available data remain retrospective, single-arm, and geographically concentrated. Direct high-quality comparative evidence between TA and AS is lacking, and TA does not eliminate several central management issues in low-risk PTMC, including occult multifocality, limited pathologic information, the need for continued surveillance, and dependence on operator expertise and institutional systems.
SummaryTA appears best understood as a selectively deployable, center-dependent intervention rather than a replacement for AS or surgery. On the basis of current literature, its most plausible present role is in carefully selected adults with biopsy-proven, low-risk intrathyroidal PTMC who decline surgery and remain unwilling or unable to pursue long-term AS, provided treatment is delivered in a high-expertise setting with structured follow-up.