Scholarlink

Purpose of Review <p>This review highlights recent advances in adrenal endocrine surgery and oncology, emphasizing progress in pathology, imaging, perioperative planning, and systemic therapy.</p> Recent Findings <p>In pathology, the World Health Organization recently refined the classifications of adrenocortical lesions as well as pheochromocytomas and paragangliomas. In radiology, new molecular imaging tracers and theranostics have advanced adrenal functional imaging. Novel applications of artificial intelligence and 3D anatomical modeling have also aided tumor diagnosis and adrenal surgery preoperative planning. In endocrine oncology, the expansion of tumor molecular profiling and the application of new targeted therapies has improved progression-free survival in patients with advanced pheochromocytomas and paragangliomas. Dual immunotherapy has modestly improved progression-free survival in patients with adrenocortical carcinoma.</p> Summary <p>Recent changes in pathologic classification, imaging analysis, and novel applications of targeted systemic therapies have transformed care of patients with adrenal tumors, shepherding surgical and endocrine oncology into an era of precision medicine.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Important Advances in Adrenal Pathologic Classification, Imaging Analysis, and Systemic Therapy: What the Contemporary Endocrine Surgeon should Know

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月26日

查看全文
  • Jennine H. Weller,
  • Eddy P. Lincango,
  • Jennifer J. Butler,
  • Ahmed Salem,
  • Khaled M. Elsayes,
  • Nancy D. Perrier

摘要

Purpose of Review

This review highlights recent advances in adrenal endocrine surgery and oncology, emphasizing progress in pathology, imaging, perioperative planning, and systemic therapy.

Recent Findings

In pathology, the World Health Organization recently refined the classifications of adrenocortical lesions as well as pheochromocytomas and paragangliomas. In radiology, new molecular imaging tracers and theranostics have advanced adrenal functional imaging. Novel applications of artificial intelligence and 3D anatomical modeling have also aided tumor diagnosis and adrenal surgery preoperative planning. In endocrine oncology, the expansion of tumor molecular profiling and the application of new targeted therapies has improved progression-free survival in patients with advanced pheochromocytomas and paragangliomas. Dual immunotherapy has modestly improved progression-free survival in patients with adrenocortical carcinoma.

Summary

Recent changes in pathologic classification, imaging analysis, and novel applications of targeted systemic therapies have transformed care of patients with adrenal tumors, shepherding surgical and endocrine oncology into an era of precision medicine.

Graphical Abstract