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Purpose of Review <p>The following review explores the recent evidence on the benefits and risks of one anastomosis gastric bypass (OAGB) and single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) with the goal of providing a balanced and up-to-date perspective on their place in modern bariatric practice with specific attention paid to weight loss outcomes, complication rates, and remission of obesity related comorbidities.</p> Recent Findings <p>Mean %EWL at 12, 24, and 36 months for OAGB were 78.8%, 83.6%, and 80.6%. Mean %EWL for SADI-S in the same period were 79.5%, 84%, and 75%. Mean 30-day complication rates were 5.8% for OAGB and 5.16% for SADI-S. Remission rates for type two diabetes and hypertension were 87.1% and 92.59% for OAGB and 86.3% and 77.5% for SADI-S.</p> Conclusion <p>OAGB and SADI-S offer durable weight loss and effective resolution of obesity related diseases with a favorable safety profile. They should more frequently be considered as primary surgical interventions for the management of obesity.</p>

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Current Status of Single Anastomosis Operations in Bariatric Surgery – The Risks and Benefits of OAGB and SADI-S

  • 期刊论文

  • 发表日期：

    2025年9月1日

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  • Gabrielle Falco,
  • Alex Dunaway,
  • Alex Clem,
  • Christopher Dyke

摘要

Purpose of Review

The following review explores the recent evidence on the benefits and risks of one anastomosis gastric bypass (OAGB) and single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) with the goal of providing a balanced and up-to-date perspective on their place in modern bariatric practice with specific attention paid to weight loss outcomes, complication rates, and remission of obesity related comorbidities.

Recent Findings

Mean %EWL at 12, 24, and 36 months for OAGB were 78.8%, 83.6%, and 80.6%. Mean %EWL for SADI-S in the same period were 79.5%, 84%, and 75%. Mean 30-day complication rates were 5.8% for OAGB and 5.16% for SADI-S. Remission rates for type two diabetes and hypertension were 87.1% and 92.59% for OAGB and 86.3% and 77.5% for SADI-S.

Conclusion

OAGB and SADI-S offer durable weight loss and effective resolution of obesity related diseases with a favorable safety profile. They should more frequently be considered as primary surgical interventions for the management of obesity.