Does Anti-Reflux Surgery Improve Outcomes in Isolated Laryngopharyngeal Reflux? A Systematic Review
摘要
Laryngopharyngeal Reflux (LPR) continues to challenge management due to its uncertain pathological mechanism, variable clinical manifestations, and inconsistent treatment outcomes. Anti Reflux surgery (ARS), specifically fundoplication, is a well described efficacious treatment for patients with proven gastroesophageal reflux disease, who fail lifestyle modification and medical therapy. However, patients with upper aerodigestive tract symptoms attributed to ‘isolated LPR,’ where there is no objective and/or symptomatic distal GORD, are a difficult cohort to provide an effective, durable and reproducible treatment. This review aims to assess the literature evidence for ARS in the treatment of patients with ‘isolated LPR’.
Recent findingsFive studies from 689 initial records met the inclusion criteria. Treatment effect was primarily evaluated through patient reported outcome measures. There was a wide range in the percentage of patients who achieved complete symptom resolution (30–91%) of LPR symptoms following laparoscopic anti-reflux surgery. There was a general trend towards greater symptom improvement in patients with combination of LPR and GORD following ARS.
SummaryThe current evidence does not show a clear benefit in ARS for the treatment of isolated LPR. Further study on the correct identification of patients with LPR are required to better predict patiets who would benefit from fundoplication.