Scholarlink

<p><i>Pongamia pinnata</i> (Linn.) is most commonly referred to as “Karanj.” It is acknowledged by many traditional medicinal systems as an effective treatment for a wide range of human ailments. Given its significance, physicochemical and marker-based HPTLC standardization were aimed for quality assessment of <i>P. pinnata</i>. The physicochemical analysis of the stem bark, root, and leaves of <i>P. pinnata</i> showed that all three parts possessed loss on drying of 11.08%, 9.89%, and 4.97% at 105&#xa0;°C, a total ash content of 9.64%, 4.14%, and 6.32%, acid-insoluble ash contents of 0.89%, 0.25%, &amp; 0.75%, alcohol soluble extractive values of 5.45%, 7.11%, &amp; 3.39%, and water extractive values of 20.13%, 12.00%, &amp; 14.96%, respectively. The marker-based HPTLC analysis was performed with a mobile phase composed of toluene: ethyl acetate (9:1, v/v). The plate was visualized at UV 254&#xa0;nm, and quantification of marker karanjin was accomplished in reflection/absorbance mode at λ 260&#xa0;nm. The HPTLC phytochemical fingerprints of each part of <i>P. pinnata</i> consisted of several peaks ranging from R<sub>f</sub> 0.12 to 0.92; the peak at R<sub>f</sub> 0.48 corresponded with the marker karanjin. It was reported that the karanjin content in the stem bark, root, and leaves of <i>P. pinnata</i> was found to be 0.23%, 0.36%, and 0.22%, respectively. The results of physicochemical, qualitative and quantitative HPTLC analysis established as an outcome of this research may be assessed for overall quality evaluation of <i>P. pinnata</i> and herbal formulations containing <i>P. pinnata</i>.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Physicochemical & Marker-Based HPTLC Standardization of Pongamia pinnata (Linn.), used in Indian System of Medicine

  • 期刊论文

  • 发表日期：

    2026年4月9日

查看全文
  • Vineet Kumar Pandey,
  • Sweta Mohan,
  • Anupam Maurya,
  • Subash Chandra Verma,
  • Raman Mohan Singh

摘要

Pongamia pinnata (Linn.) is most commonly referred to as “Karanj.” It is acknowledged by many traditional medicinal systems as an effective treatment for a wide range of human ailments. Given its significance, physicochemical and marker-based HPTLC standardization were aimed for quality assessment of P. pinnata. The physicochemical analysis of the stem bark, root, and leaves of P. pinnata showed that all three parts possessed loss on drying of 11.08%, 9.89%, and 4.97% at 105 °C, a total ash content of 9.64%, 4.14%, and 6.32%, acid-insoluble ash contents of 0.89%, 0.25%, & 0.75%, alcohol soluble extractive values of 5.45%, 7.11%, & 3.39%, and water extractive values of 20.13%, 12.00%, & 14.96%, respectively. The marker-based HPTLC analysis was performed with a mobile phase composed of toluene: ethyl acetate (9:1, v/v). The plate was visualized at UV 254 nm, and quantification of marker karanjin was accomplished in reflection/absorbance mode at λ 260 nm. The HPTLC phytochemical fingerprints of each part of P. pinnata consisted of several peaks ranging from Rf 0.12 to 0.92; the peak at Rf 0.48 corresponded with the marker karanjin. It was reported that the karanjin content in the stem bark, root, and leaves of P. pinnata was found to be 0.23%, 0.36%, and 0.22%, respectively. The results of physicochemical, qualitative and quantitative HPTLC analysis established as an outcome of this research may be assessed for overall quality evaluation of P. pinnata and herbal formulations containing P. pinnata.