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<p>Seagrass is abundant in bioactive compounds like vitamins and minerals. The study focused on utilization of <i>C. serrulata</i> to synthesize the silica nanoparticles through a green chemistry approach. The bioactive compounds of seagrass act as capping and reducing agents in fabrication of nanoparticles. The physical and chemical properties of <i>C. serrulata</i>-mediated silica nanoparticles (NPs) were examined using UV-Vis spectroscopy, FTIR, XRD, FESEM-EDX, and TGA analysis. DPPH assay assessed the free radical scavenging activity of <i>C. serrulata-</i>mediated silica NPs. UV-Vis spectroscopy revealed a peak at 300&#xa0;nm, indicating silica nanoparticle formation. FTIR analysis showed various functional groups like Si-OH stretch, H-O-H stretch, Si-O-Si bond, and SiO<sub>2</sub> bond. XRD analysis determined the function of amorphous silica nanoparticles. FESEM analysis displayed spherical-shaped silica nanoparticles. TGA analysis demonstrated the thermal stability of <i>C. serrulata</i>-mediated silica NPs. DPPH assay concluded that as-synthesized nanoparticles show the significant scavenging activity with IC<sub>50</sub> value of 18.50&#xa0;µg/mL, which corresponding its important antioxidant properties with potential health benefits. The antioxidant potential of <i>C. serrulata</i>-mediated silica NPs may use in nanomedicine field to produce the novel drug.</p>

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Fabrication and Characterization of Cymodocea serrulata Extract-Mediated Silica Nanoparticles with Antioxidant Properties

  • 期刊论文

  • 发表日期：

    2025年1月28日

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  • Karungan Selvaraj Vijai Selvaraj,
  • Rajiv Periakaruppan,
  • Abhishekh K. T.,
  • Kuppusamy Sathishkumar,
  • Nishanth Mohan Das

摘要

Seagrass is abundant in bioactive compounds like vitamins and minerals. The study focused on utilization of C. serrulata to synthesize the silica nanoparticles through a green chemistry approach. The bioactive compounds of seagrass act as capping and reducing agents in fabrication of nanoparticles. The physical and chemical properties of C. serrulata-mediated silica nanoparticles (NPs) were examined using UV-Vis spectroscopy, FTIR, XRD, FESEM-EDX, and TGA analysis. DPPH assay assessed the free radical scavenging activity of C. serrulata-mediated silica NPs. UV-Vis spectroscopy revealed a peak at 300 nm, indicating silica nanoparticle formation. FTIR analysis showed various functional groups like Si-OH stretch, H-O-H stretch, Si-O-Si bond, and SiO2 bond. XRD analysis determined the function of amorphous silica nanoparticles. FESEM analysis displayed spherical-shaped silica nanoparticles. TGA analysis demonstrated the thermal stability of C. serrulata-mediated silica NPs. DPPH assay concluded that as-synthesized nanoparticles show the significant scavenging activity with IC50 value of 18.50 µg/mL, which corresponding its important antioxidant properties with potential health benefits. The antioxidant potential of C. serrulata-mediated silica NPs may use in nanomedicine field to produce the novel drug.