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Purpose <p>Melioidosis is a serious infection caused by <i>Burkholderia pseudomallei</i>, a bacterium found in soil, water, and plants in tropical and subtropical regions. The infection can present with a range of clinical symptoms and may be fatal without appropriate treatment.</p> Case presentation <p>We present four confirmed cases of melioidosis in patients with a history as tourists travelling to endemic areas. These cases illustrate the diverse clinical manifestations of the infection, ranging from respiratory tract involvement to multiple organ abscesses, as well as the therapeutic approaches employed.</p> Conclusion <p>Melioidosis is a severe infection with variable clinical presentations, including fever, night sweats, weight loss, dyspnoea, and abscess formation at different sites. The broad spectrum of symptoms complicates diagnosis. Therefore, melioidosis should be considered in returning travellers from endemic regions presenting with compatible clinical features. Prolonged antibiotic treatment is essential for effective infection control.</p>

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Melioidosis imported to Northern Germany: a case report series

  • 期刊论文

  • 发表日期：

    2025年11月28日

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  • Dorothea Ekoka Mbassi,
  • Aiman Gamal Abdelrahim,
  • Ilka Grewe,
  • Pia M. Michelitsch,
  • Annette Hennigs,
  • Flaminia Olearo,
  • Marylyn M. Addo,
  • Michael Ramharter,
  • Sabine Jordan,
  • Stefan Schmiedel

摘要

Purpose

Melioidosis is a serious infection caused by Burkholderia pseudomallei, a bacterium found in soil, water, and plants in tropical and subtropical regions. The infection can present with a range of clinical symptoms and may be fatal without appropriate treatment.

Case presentation

We present four confirmed cases of melioidosis in patients with a history as tourists travelling to endemic areas. These cases illustrate the diverse clinical manifestations of the infection, ranging from respiratory tract involvement to multiple organ abscesses, as well as the therapeutic approaches employed.

Conclusion

Melioidosis is a severe infection with variable clinical presentations, including fever, night sweats, weight loss, dyspnoea, and abscess formation at different sites. The broad spectrum of symptoms complicates diagnosis. Therefore, melioidosis should be considered in returning travellers from endemic regions presenting with compatible clinical features. Prolonged antibiotic treatment is essential for effective infection control.