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<p>Human metapneumovirus (hMPV) is a significant cause of respiratory infections worldwide, particularly in young children, the elderly, and immunocompromised individuals. Since its discovery in 2001, hMPV has been recognized as a major contributor to acute respiratory tract infections, along with respiratory syncytial virus (RSV) and influenza. This review explores the virology, epidemiology, pathogenesis, clinical manifestations, diagnostic methods, and recent advances in therapeutic and preventive strategies for hMPV infection. By consolidating current knowledge, we aim to highlight the importance of hMPV in public health and the need for continued research to address its clinical and economic burdens.</p>

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Human metapneumovirus (hMPV): the virus who came with the common cold

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年8月12日

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  • Varun Pandey,
  • Preeti Shahi,
  • George Kolios,
  • Muhammad Ikhtear Uddin,
  • Michail Spathakis,
  • Alexandra R. Collins,
  • Vasilis Paspaliaris,
  • Ambak Kumar Rai

摘要

Human metapneumovirus (hMPV) is a significant cause of respiratory infections worldwide, particularly in young children, the elderly, and immunocompromised individuals. Since its discovery in 2001, hMPV has been recognized as a major contributor to acute respiratory tract infections, along with respiratory syncytial virus (RSV) and influenza. This review explores the virology, epidemiology, pathogenesis, clinical manifestations, diagnostic methods, and recent advances in therapeutic and preventive strategies for hMPV infection. By consolidating current knowledge, we aim to highlight the importance of hMPV in public health and the need for continued research to address its clinical and economic burdens.