<p>Response Surface Methodology (RSM) was used to maximize the removal of Ramazol Brilliant Violet-5R (RBV-5R) dye using Cement Kiln Dust (CKD) and Coriander Seeds (CS) separately. To investigate how initial dye concentration, pH, adsorbent dosage, and contact time affected the dye removal effectiveness, a central composite design (CCD) was employed. 31 experiments' levels and a few chosen variables were established. Minitab (version 17.1) was utilized to facilitate the regression and graphical analysis of the collected data. It was discovered that raising the starting pH, adsorbent dosage, and contact duration for both adsorbents while decreasing the initial dye concentration increased the dye removal effectiveness. The analysis of variance (ANOVA) findings for RBV5R dye removal showed a high R² value of 98.81 percent for CS and 96.69 percent for CKD, respectively, suggesting that the accuracy of the polynomial model is satisfactory. The model-predicted result (95.18–97.83%) for both CS and CKD was almost identical to the experimentally observed dye removal efficiency at the optimal point, which ranged from 97.120 to 98.470 percent.</p>