<p>Reducing carbon emissions due to increasing climate concerns has become important at every stage of the supply chain line, as it is in every sector. Many activities take place in the supply chain processes and it takes serious work for these activities to be in line with the net zero carbon strategy. This paper addresses the challenges that are preventing the supply chain from achieving its net zero carbon target. Challenges addressed; It is categorized as environmental challenges, financial and economic challenges, organizational challenges, social and consumer challenges, technical and technological challenges, and administrative challenges. Depending on the 6 main categories determined, 24 sub-challenges are determined and the network structure, relations and rankings of the determined challenges are determined by the Analytical Network Process (ANP) method, one of the Multi-Criteria Decision Making methods. The risks of the challenges identified by the ANP-based Failure Mode and Effect Analysis (FMEA) are also listed. According to the ANP and ANP based FMEA methods, it is seen that the riskiest results and the most important challenges are Financial and Economic challenges and Technical and Technological challenges, respectively. According to the ANP, the most important challenges are respectively “Lack of technical competence and field experts”, “Lack of resources”, and “High initial investment cost”. According to the ANP based FMEA, the most important challenges are “Lack of resources”, “Lack of technical competence and field experts” and “Uncertain long-term economic return/payback periods and investment risks”, respectively. In the study, it is thought that the relationships and rankings determined will be a roadmap to reach net zero carbon targets in supply chains.</p>