<p><i>Ehretia</i> Linn., a member of the family Boraginaceae, is a diverse genus of about 66 species, found primarily in tropical Asia and Africa, Europe, North America, and Australia. Various parts of the constituent plants have been utilized independently as herbal remedies in different parts of the world. The genus has been found to possess flavonoids, steroids, lignans, phenolic acids, triterpenoids, quinones, nitrile glycosides, and pyrrolizidine alkaloids. Numerous species have been studied for their anti-inflammatory, anti-bacterial, antioxidant, and anti-diabetic properties. The rich chemistry and immense pharmacological potential of the genus <i>Ehretia</i> invites for a comprehensive and critical review of various aspects of the genus. Herein, we have attempted to present the first ever review of this important genus, with the help of relevant literature, collected using the keywords “<i>Ehretia</i>”, “phytochemistry”, “pharmacology”, “medicinal uses”, in scientific databases such as “Google Scholar”, “PubMed”, “Hindawi” etc., till the end of November 2024. Chem Draw software was used for drawing structures of the molecules. About 76 compounds have been isolated from various species of the genus, possessing interesting biological activities, such as anti-cancer, anti-inflammatory, anti-diabetic, anti-venom, anti-microbial, anti-oxidant etc.</p>

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A comprehensive review on ethnopharmacological uses and phytochemistry of genus Ehretia Linn

  • Zeenat Waris,
  • Asad Ali Khan,
  • Salman Zafar

摘要

Ehretia Linn., a member of the family Boraginaceae, is a diverse genus of about 66 species, found primarily in tropical Asia and Africa, Europe, North America, and Australia. Various parts of the constituent plants have been utilized independently as herbal remedies in different parts of the world. The genus has been found to possess flavonoids, steroids, lignans, phenolic acids, triterpenoids, quinones, nitrile glycosides, and pyrrolizidine alkaloids. Numerous species have been studied for their anti-inflammatory, anti-bacterial, antioxidant, and anti-diabetic properties. The rich chemistry and immense pharmacological potential of the genus Ehretia invites for a comprehensive and critical review of various aspects of the genus. Herein, we have attempted to present the first ever review of this important genus, with the help of relevant literature, collected using the keywords “Ehretia”, “phytochemistry”, “pharmacology”, “medicinal uses”, in scientific databases such as “Google Scholar”, “PubMed”, “Hindawi” etc., till the end of November 2024. Chem Draw software was used for drawing structures of the molecules. About 76 compounds have been isolated from various species of the genus, possessing interesting biological activities, such as anti-cancer, anti-inflammatory, anti-diabetic, anti-venom, anti-microbial, anti-oxidant etc.