Scholarlink

<p>In this work, a composite material consisting of copper oxide nanoparticles (CuONPs) and reduced graphene oxide (rGO) was fabricated by a two-step reduction method. The CuONPs-rGO composite material was characterized by fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and electrochemical impedance spectroscopy (EIS). The electrochemical behavior of cilnidipine (CLP) at CuONPs-rGO coated glassy carbon electrode (CuONPs-rGO <b>/</b>GCE) was discussed. The results demonstrated that CuONPs-rGO composite film enhanced the electrochemical activity of the electrode. Additionally, the electrode performance of CuONPs-rGO<b>/</b>GCE was investigated in detail, which exhibited high selectivity and preferable stability since the deviation was less than ± 5%. Within the range from 8.0 × 10⁻⁸ to 3.0 × 10⁻<sup>5</sup> M, the variation of the peak current increased linearly with CLP concentration. CuONPs-rGO<b>/</b>GCE as a newly electrochemical sensor, it can be employed to detect the content of CLP in pharmaceutical samples. The recovery for CLP detection ranges from 98.44% to 103.57%, indicating that the fabricated CuONPs-rGO<b>/</b>GCE sensor is suitable for the application in pharmaceutical analysis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A sensitive cilnidipine sensor based on copper oxide nano-particles and reduced graphene oxide coated glassy carbon electrode

  • 期刊论文

  • 发表日期：

    2026年3月9日

查看全文
  • Yingliang Wei,
  • Anting Wang,
  • Jiarun Huang,
  • Chunlai Wu

摘要

In this work, a composite material consisting of copper oxide nanoparticles (CuONPs) and reduced graphene oxide (rGO) was fabricated by a two-step reduction method. The CuONPs-rGO composite material was characterized by fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and electrochemical impedance spectroscopy (EIS). The electrochemical behavior of cilnidipine (CLP) at CuONPs-rGO coated glassy carbon electrode (CuONPs-rGO /GCE) was discussed. The results demonstrated that CuONPs-rGO composite film enhanced the electrochemical activity of the electrode. Additionally, the electrode performance of CuONPs-rGO/GCE was investigated in detail, which exhibited high selectivity and preferable stability since the deviation was less than ± 5%. Within the range from 8.0 × 10⁻⁸ to 3.0 × 10⁻5 M, the variation of the peak current increased linearly with CLP concentration. CuONPs-rGO/GCE as a newly electrochemical sensor, it can be employed to detect the content of CLP in pharmaceutical samples. The recovery for CLP detection ranges from 98.44% to 103.57%, indicating that the fabricated CuONPs-rGO/GCE sensor is suitable for the application in pharmaceutical analysis.