Scholarlink

<p>Chronic active Epstein-Barr virus is a rare but severe condition characterized by persistent Epstein-Barr virus activation, leading to chronic lymphoproliferation, significant morbidity, and mortality. We report the case of a 34-year-old male with autosomal dominant polycystic kidney disease who achieved chronic active Epstein-Barr virus remission through hematopoietic stem cell transplantation in childhood. Despite long-term remission, the patient developed end-stage renal disease and underwent ABO-incompatible living-donor kidney transplantation. Post-transplant monitoring over 7 months revealed no major complications, including post-transplant lymphoproliferative disorder or rejection, despite transient Epstein-Barr virus-DNA positivity. This case underscores the feasibility of kidney transplantation in chronic active Epstein-Barr virus survivors with careful immunosuppressive management. It also highlights the critical need for vigilant long-term surveillance to mitigate the risks of malignancies and viral reactivation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Kidney transplantation after chronic active Epstein-Barr virus infection remission

  • 期刊论文

  • 发表日期：

    2026年2月13日

查看全文
  • Yuki Tashiro,
  • Yoji Hyodo,
  • Satoshi Kitamura,
  • Takahito Endo,
  • Shun Nishioka,
  • Naoki Yokoyama,
  • Kotaro Suzuki,
  • Takuto Hara,
  • Koji Chiba,
  • Hideaki Miyake

摘要

Chronic active Epstein-Barr virus is a rare but severe condition characterized by persistent Epstein-Barr virus activation, leading to chronic lymphoproliferation, significant morbidity, and mortality. We report the case of a 34-year-old male with autosomal dominant polycystic kidney disease who achieved chronic active Epstein-Barr virus remission through hematopoietic stem cell transplantation in childhood. Despite long-term remission, the patient developed end-stage renal disease and underwent ABO-incompatible living-donor kidney transplantation. Post-transplant monitoring over 7 months revealed no major complications, including post-transplant lymphoproliferative disorder or rejection, despite transient Epstein-Barr virus-DNA positivity. This case underscores the feasibility of kidney transplantation in chronic active Epstein-Barr virus survivors with careful immunosuppressive management. It also highlights the critical need for vigilant long-term surveillance to mitigate the risks of malignancies and viral reactivation.