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<p>Goreisan is an herbal medicine that regulates water metabolism, exerting a diuretic effect that does not alter urine volume in dehydrated conditions but increases urine output in edematous conditions without affecting plasma electrolyte levels, thereby demonstrating an anti-edema action. We report a case of severe lupus nephritis (LN) accompanied by nephrotic syndrome (NS) in which Goreisan proved effective in managing intractable edema. Goreisan is considered potentially beneficial for controlling intractable edema associated with nephritic NS, including severe LN.</p>

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Successful treatment of intractable edema with Goreisan in severe lupus nephritis with nephrotic syndrome: a case report

  • 期刊论文

  • 发表日期：

    2026年2月5日

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  • Masaki Shimizu,
  • Norimasa Tada,
  • Hitoshi Irabu,
  • Miki Murakoshi,
  • Tomohiro Udagawa

摘要

Goreisan is an herbal medicine that regulates water metabolism, exerting a diuretic effect that does not alter urine volume in dehydrated conditions but increases urine output in edematous conditions without affecting plasma electrolyte levels, thereby demonstrating an anti-edema action. We report a case of severe lupus nephritis (LN) accompanied by nephrotic syndrome (NS) in which Goreisan proved effective in managing intractable edema. Goreisan is considered potentially beneficial for controlling intractable edema associated with nephritic NS, including severe LN.