Purpose of Review <p>This review summarizes current knowledge on precision nutrition in gestational obesity management and outlines priorities for future research and implementation.</p> Recent Findings <p>We summarize evidence on key factors (i.e., observable traits, social determinants of health, behavioral factors, clinical biomarkers, tissue-specific features, molecular-level data) that can be assessed and targeted within a precision nutrition approach for managing gestational obesity. Recent studies highlight obesity classes, behavioral-metabolic obesity phenotyping (hungry brain, emotional hunger, hungry gut) and the maternal metabolic milieu as interesting targets. Women’s and healthcare professionals’ (end-users) needs and perceptions as well as digital infrastructure requirements need further exploration.</p> Summary <p>There is promise for more precision-based nutrition in optimizing gestational obesity management moving away from current one-size-fits all approaches. However, additional research is required to determine appropriate precision‑based nutrition approaches, evaluate their efficacy and cost‑effectiveness, and develop strategies for their implementation in routine care.</p>