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Purpose of Review <p>In this review, the promising benefits of coffee in terms of its composition, anticancer mechanisms, and effects on digestive system cancers are highlighted and suggestions for future research are given.</p> Recent Findings <p>Coffee is one of the most widely consumed beverages in the world. Chlorogenic acid, caffeine, cafestol, kahweol, phenolic compounds, alkaloids, trigonelline, and other secondary metabolites in its composition have positive effects on health. Colorectal cancer, esophageal cancer, liver cancer, gastric cancer, and pancreatic cancer are among the most common cancers of the digestive system worldwide. Cancer risk is increasingly influenced by dietary factors.</p> Summary <p>Coffee has been linked to potential protective effects against cancer due to its antioxidant, anti-inflammatory, antifibrotic, and antiangiogenic properties, as it contains over 1,000 bioactive compounds. However, there are inconsistent findings concerning coffee consumption and the risk of digestive tract cancers and more clinical studies with larger samples are needed.</p>

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Coffee Consumption and Its Potential Implications for Digestive Tract Carcinogenesis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月30日

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  • Nevin Sanlier,
  • Ebru Ozler

摘要

Purpose of Review

In this review, the promising benefits of coffee in terms of its composition, anticancer mechanisms, and effects on digestive system cancers are highlighted and suggestions for future research are given.

Recent Findings

Coffee is one of the most widely consumed beverages in the world. Chlorogenic acid, caffeine, cafestol, kahweol, phenolic compounds, alkaloids, trigonelline, and other secondary metabolites in its composition have positive effects on health. Colorectal cancer, esophageal cancer, liver cancer, gastric cancer, and pancreatic cancer are among the most common cancers of the digestive system worldwide. Cancer risk is increasingly influenced by dietary factors.

Summary

Coffee has been linked to potential protective effects against cancer due to its antioxidant, anti-inflammatory, antifibrotic, and antiangiogenic properties, as it contains over 1,000 bioactive compounds. However, there are inconsistent findings concerning coffee consumption and the risk of digestive tract cancers and more clinical studies with larger samples are needed.