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<p>The value of lymph-node dissection in prostate cancer remains a&#xa0;subject of ongoing debate. To date, no study has provided conclusive evidence of a&#xa0;long-term oncological benefit. In this context, lymph-node dissection primarily serves a&#xa0;diagnostic purpose. The introduction of prostate-specific membrane antigen (PSMA) PET/CT imaging, characterized by its high sensitivity for detecting lymph-node metastases, increasingly approximates the diagnostic accuracy of pelvic lymph-node dissection (PLND). This technological advancement raises important ethical and clinical considerations regarding the necessity and justification of routinely performing an invasive procedure such as PLND in an era where high-quality, non-invasive imaging is readily available.</p>

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Is het doen van een pelviene lymfeklierdissectie bij prostaatkanker nog wel gerechtvaardigd nu PSMA PET/CT breed beschikbaar is?

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月2日

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  • André N. Vis,
  • Bernard H. E. Jansen-Stensland

摘要

The value of lymph-node dissection in prostate cancer remains a subject of ongoing debate. To date, no study has provided conclusive evidence of a long-term oncological benefit. In this context, lymph-node dissection primarily serves a diagnostic purpose. The introduction of prostate-specific membrane antigen (PSMA) PET/CT imaging, characterized by its high sensitivity for detecting lymph-node metastases, increasingly approximates the diagnostic accuracy of pelvic lymph-node dissection (PLND). This technological advancement raises important ethical and clinical considerations regarding the necessity and justification of routinely performing an invasive procedure such as PLND in an era where high-quality, non-invasive imaging is readily available.