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<p><i>Ficus hispida</i> L.f. is a hairy shrub, belonging to Moraceae family, has been used extensively in various regions of the world due to high nutritional and ethnopharmacological importance. Several diseases like leukoderma, vitiligo and diarrhoea are among the few ones to be treated by various traditional medicines obtained from aerial parts of this plant. This review aims to provide a narrative comment about botany, microscopy, ethnopharmacological values, phytochemistry, preclinical pharmacological activities, toxicity and pharmacokinetic parameters of <i>Ficus hispida</i> L.f., which will be proven crucial for gaining new therapeutic insights. All the data have been retrieved various electronic scholarly devices including Web of Science, Scopus, Science Direct, PubMed and Google Scholar. A detailed literature review from various books were conducted. <i>Ficus hispida</i> L.f. is used by people of South east Asian countries for its numerous ethnopharmacological values. Approximately 72 different phytochemicals have been identified from various extracts of the plant parts, belonging to alkanes, alkaloids, coumarins, glycosides, flavonoids, steroids or terpenoids class. Preclinical pharmacological effects of crude plant extracts and some isolated phytochemicals have also been reported against cancer, diabetes mellitus, epilepsy, hyperlipidaemia, and so on. Most reports lack a proper establishment of mechanistic pathway. <i>Ficus hispida</i> L.f. is considered as one of the most significant medicinal plants for its traditional and preclinical pharmacological effects. However, absence of mechanistic interpretation from majority of preclinical studies and clinical trials lead to the requirement of more extensive research to fulfil the gaps and use to cure ailments.</p> Graphical abstract

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A narrative review emphasizing on traditional, phytochemical and pharmacological effects of Ficus hispida L.f

  • 期刊论文

  • 发表日期：

    2026年7月8日

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  • Subhadas Chatterjee,
  • Niranjan Panda,
  • Sankhadip Bose,
  • Subas Chandra Dinda

摘要

Ficus hispida L.f. is a hairy shrub, belonging to Moraceae family, has been used extensively in various regions of the world due to high nutritional and ethnopharmacological importance. Several diseases like leukoderma, vitiligo and diarrhoea are among the few ones to be treated by various traditional medicines obtained from aerial parts of this plant. This review aims to provide a narrative comment about botany, microscopy, ethnopharmacological values, phytochemistry, preclinical pharmacological activities, toxicity and pharmacokinetic parameters of Ficus hispida L.f., which will be proven crucial for gaining new therapeutic insights. All the data have been retrieved various electronic scholarly devices including Web of Science, Scopus, Science Direct, PubMed and Google Scholar. A detailed literature review from various books were conducted. Ficus hispida L.f. is used by people of South east Asian countries for its numerous ethnopharmacological values. Approximately 72 different phytochemicals have been identified from various extracts of the plant parts, belonging to alkanes, alkaloids, coumarins, glycosides, flavonoids, steroids or terpenoids class. Preclinical pharmacological effects of crude plant extracts and some isolated phytochemicals have also been reported against cancer, diabetes mellitus, epilepsy, hyperlipidaemia, and so on. Most reports lack a proper establishment of mechanistic pathway. Ficus hispida L.f. is considered as one of the most significant medicinal plants for its traditional and preclinical pharmacological effects. However, absence of mechanistic interpretation from majority of preclinical studies and clinical trials lead to the requirement of more extensive research to fulfil the gaps and use to cure ailments.

Graphical abstract