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<p>In traditional Persian medicine, health and disease are closely tied to ‘temperament’, a holistic concept related to an individual’s physical, physiological, and psychological characteristics. Studies exploring the link between temperament and modern scientific concepts are increasingly promising. This study aims to examine the relationship between temperament and pupillary light reflex (PLR). To achieve this goal, PLR signals were recorded from participants, and temperament was assessed using a validated questionnaire categorizing individuals along cold-warm and dry–wet orthogonal dimensions. Results demonstrate that individuals with warmer and/or drier temperaments exhibit significantly shorter PLR latency and faster pupil constriction and dilation dynamics. These findings highlight the correlation between temperament and autonomic nervous system (ANS) state, supporting the integration of temperament-based assessments into personalized healthcare frameworks.</p>

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The relationship between pupillary light response (PLR) and temperament in traditional Persian medicine (TPM)

  • 期刊论文

  • 发表日期：

    2025年3月25日

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  • Mahdi Kafaee,
  • Fatemeh Moazen,
  • Maryam Saidi

摘要

In traditional Persian medicine, health and disease are closely tied to ‘temperament’, a holistic concept related to an individual’s physical, physiological, and psychological characteristics. Studies exploring the link between temperament and modern scientific concepts are increasingly promising. This study aims to examine the relationship between temperament and pupillary light reflex (PLR). To achieve this goal, PLR signals were recorded from participants, and temperament was assessed using a validated questionnaire categorizing individuals along cold-warm and dry–wet orthogonal dimensions. Results demonstrate that individuals with warmer and/or drier temperaments exhibit significantly shorter PLR latency and faster pupil constriction and dilation dynamics. These findings highlight the correlation between temperament and autonomic nervous system (ANS) state, supporting the integration of temperament-based assessments into personalized healthcare frameworks.