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Introduction <p>Hair thinning is a multifactorial issue affecting women across life stages, frequently associated with reduced linear hair growth rate (LHGR). Hair growth nutraceuticals (HGNs) formulated with variations of a botanical-based multi-targeting complex are designed to address key root causes of hair thinning specific to different life stages. While prior studies have shown improvements in hair growth, quality, and fiber thickness, quantitative changes in LHGR have not been previously evaluated.</p> Methods <p>This prospective, 6-month study enrolled 180 women aged 18–70 years, assigned to one of four HGNs tailored for women at different life stages and diets. All subjects had self-reported hair thinning, confirmed by the study dermatologist. Participants were assessed at days 0, 90, and 180. Each timepoint included standardized hair clipping followed by objective analysis using Canfield HairMetrix<sup>®</sup> 48 h later, which included LHGR, hair counts, and anagen/telogen phase assessment. Self-assessment questionnaires were also completed at each post-baseline timepoint.</p> Results <p>A total of 150 participants completed the study per protocol. Daily ingestion of the tailored HGNs resulted in statistically significant increases in LHGR at both day 90 and day 180 compared with baseline across all four groups. Anagen hair counts rose significantly across the study duration in all groups, alongside gains in total and terminal hair counts. Total scalp coverage also significantly increased compared with baseline. The changes in hair parameters were corroborated with high agreement regarding improvements in hair parameters in the subject questionnaire.</p> Conclusions <p>This study demonstrates that consumption of these HGNs is associated with significant improvements in LHGR and other objective hair parameters in women experiencing hair thinning. These findings support the use of targeted HGNs as an effective strategy to enhance hair growth rate and overall hair health across different life stages.</p> Trial registration <p>ClinicalTrials.gov identifier: NCT06376409.</p>

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A 6-Month Prospective, Open-Label, Randomized Study Showing Increased Hair Growth Rate in Women Using Multi-Targeting Hair Growth Nutraceuticals

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月14日

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  • Rubaina Dang,
  • Raja K. Sivamani,
  • Adina Hazan,
  • Isabelle Raymond

摘要

Introduction

Hair thinning is a multifactorial issue affecting women across life stages, frequently associated with reduced linear hair growth rate (LHGR). Hair growth nutraceuticals (HGNs) formulated with variations of a botanical-based multi-targeting complex are designed to address key root causes of hair thinning specific to different life stages. While prior studies have shown improvements in hair growth, quality, and fiber thickness, quantitative changes in LHGR have not been previously evaluated.

Methods

This prospective, 6-month study enrolled 180 women aged 18–70 years, assigned to one of four HGNs tailored for women at different life stages and diets. All subjects had self-reported hair thinning, confirmed by the study dermatologist. Participants were assessed at days 0, 90, and 180. Each timepoint included standardized hair clipping followed by objective analysis using Canfield HairMetrix® 48 h later, which included LHGR, hair counts, and anagen/telogen phase assessment. Self-assessment questionnaires were also completed at each post-baseline timepoint.

Results

A total of 150 participants completed the study per protocol. Daily ingestion of the tailored HGNs resulted in statistically significant increases in LHGR at both day 90 and day 180 compared with baseline across all four groups. Anagen hair counts rose significantly across the study duration in all groups, alongside gains in total and terminal hair counts. Total scalp coverage also significantly increased compared with baseline. The changes in hair parameters were corroborated with high agreement regarding improvements in hair parameters in the subject questionnaire.

Conclusions

This study demonstrates that consumption of these HGNs is associated with significant improvements in LHGR and other objective hair parameters in women experiencing hair thinning. These findings support the use of targeted HGNs as an effective strategy to enhance hair growth rate and overall hair health across different life stages.

Trial registration

ClinicalTrials.gov identifier: NCT06376409.