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<p>In this paper, we develop and analyze a compartmental model capturing both direct and indirect transmission pathways of <i>Campylobacter</i> spp. Optimal control theory is employed to evaluate the impact and cost-effectiveness of multiple intervention strategies, including vector control, food hygiene improvements, and public health education. Sensitivity analysis identifies the key epidemiological drivers of transmission, helping to guide the efficient allocation of resources. Numerical simulations comparing single and combined control strategies reveal that integrating sanitation, insecticide use, and environmental hygiene is the most cost-effective approach in resource-limited settings. The results provide quantitative guidance for policymakers and public health practitioners seeking integrated strategies to reduce the burden of Campylobacteriosis.</p>

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Assessing Intervention Strategies to Mitigate Campylobacteriosis Dynamics: An Optimal Control Analysis and Applications

  • 期刊论文

  • 发表日期：

    2026年2月20日

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  • C. W. Chukwu,
  • J. O. Akanni,
  • C. E. Madubueze,
  • M. O. Nnakwe

摘要

In this paper, we develop and analyze a compartmental model capturing both direct and indirect transmission pathways of Campylobacter spp. Optimal control theory is employed to evaluate the impact and cost-effectiveness of multiple intervention strategies, including vector control, food hygiene improvements, and public health education. Sensitivity analysis identifies the key epidemiological drivers of transmission, helping to guide the efficient allocation of resources. Numerical simulations comparing single and combined control strategies reveal that integrating sanitation, insecticide use, and environmental hygiene is the most cost-effective approach in resource-limited settings. The results provide quantitative guidance for policymakers and public health practitioners seeking integrated strategies to reduce the burden of Campylobacteriosis.