Chemoimmunotherapy in Non-small Cell Lung Cancer Control
摘要
The term cancer is generally used to refer to a large group of diseases. Neoplastic or cancerous cells grow and divide in an uncontrolled manner and, as a result, form tumours that progressively increase in size. There are different types of cancer which are categorised according to the type of tissue or fluid originated from inside the body. We incorporate chemotherapeutic agents into a mathematical model of non-small cell lung cancer interacting with immune cells. The immune system cells included in the model are composed of macrophages and cytotoxic lymphocytes. In our model, tumour infiltrating lymphocyte therapy is also considered. In this work, we show how pulsed chemotherapy combined with immunotherapy, known as chemoimmunotherapy, can improve survival outcomes in the treatment of non-small cell lung cancer.