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<p>Titanium dioxide nanoparticles (TiO<sub>2</sub>NPs) exhibit optical, electrical, and magnetic properties and are potential candidates for biomedical uses. The cytotoxicity comparison among undoped as well as iron-doped TiO<sub>2</sub>NPs is supported by the current study. The antibacterial test was also conducted for five different bacteria. Pure and iron-doped TiO<sub>2</sub>NPs were synthesized using titanium isopropoxide and iron nitrate nonahydrate as precursors using the co-precipitation method. The synthesized TiO<sub>2</sub>NPs were characterized by XRD (X-ray diffraction), UV-Vis (UV-visible diffuse reflectance spectroscopy), EDAX (energy dispersive X-ray spectroscopy) analysis, and FTIR (Fourier transform infrared spectroscopy) analysis. XRD examination revealed a shift in peak when TiO<sub>2</sub> is doped with iron. EDAX analysis verified that (Fe<sup>3+</sup>) iron particles were present in the TiO<sub>2</sub> crystal structure. Band gap energy was calculated from UV-Vis, and it was confirmed that with an increase in doping concentration, band gap energy seems to decrease. FTIR analysis established the presence of different functional groups within TiO<sub>2</sub>NPs. The in-vitro cytotoxic effect was determined using the MTT assay method. The study showed that the iron-doped TiO<sub>2</sub>NPs are comparatively less cytotoxic than pure TiO<sub>2</sub>NPs.</p>

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Enhanced Viability of Iron-Doped Titanium Dioxide Nanoparticles with Antibacterial Efficacy

  • 期刊论文

  • 发表日期：

    2025年1月27日

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  • N. G. Jitha,
  • K. Deepa,
  • N. Ayana

摘要

Titanium dioxide nanoparticles (TiO2NPs) exhibit optical, electrical, and magnetic properties and are potential candidates for biomedical uses. The cytotoxicity comparison among undoped as well as iron-doped TiO2NPs is supported by the current study. The antibacterial test was also conducted for five different bacteria. Pure and iron-doped TiO2NPs were synthesized using titanium isopropoxide and iron nitrate nonahydrate as precursors using the co-precipitation method. The synthesized TiO2NPs were characterized by XRD (X-ray diffraction), UV-Vis (UV-visible diffuse reflectance spectroscopy), EDAX (energy dispersive X-ray spectroscopy) analysis, and FTIR (Fourier transform infrared spectroscopy) analysis. XRD examination revealed a shift in peak when TiO2 is doped with iron. EDAX analysis verified that (Fe3+) iron particles were present in the TiO2 crystal structure. Band gap energy was calculated from UV-Vis, and it was confirmed that with an increase in doping concentration, band gap energy seems to decrease. FTIR analysis established the presence of different functional groups within TiO2NPs. The in-vitro cytotoxic effect was determined using the MTT assay method. The study showed that the iron-doped TiO2NPs are comparatively less cytotoxic than pure TiO2NPs.