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Background <p>Laser technologies have led to the development of nanomaterials, which, in turn, has opened new horizons in preventive dentistry applications, especially in combating bacteria that cause tooth decay. Diamond nanoparticles were chosen and found to be promising materials due to their unique physical and biological properties.</p> Objectives <p>This study aims to evaluate the laser wavelength (1064 nm vs. 532 nm) on the synthesis, characterization, and antibacterial effectiveness of DNPs against <i>Streptococcus mutans</i> and its effect on the properties and behavior of prepared diamond nanoparticles, their characterization and effectiveness against bacteria causing dental caries.</p> Materials and methods <p>Diamond nanoparticles were synthesized using the laser ablation in liquid (PLAL) technique using an Nd:YAG laser at two different wavelengths. The optical and structural properties of the prepared particles were analyzed using UV–Vis absorption spectroscopy, zeta potential measurement, X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM). The antibacterial activity against (<i>S. mutans)</i> and cytotoxicity was evaluated to ensure their safety for biouse was also tested.</p> Results <p>The particles prepared at 532 nm showed a blue shift in the absorption spectrum, indicating high stability in the colloidal suspension with a surface potential of −30.1 mV. XRD patterns revealed the presence of a crystalline diamond structure, particularly at the (111) and (220) planes. TEM and FESEM images showed that the particles prepared at 532 nm were smaller (3–45 nm) and, compared to the particles prepared at 1064 nm, were found to be more homogeneous, less agglomerated, and more homogeneous. The results also demonstrated that their toxicity was within acceptable limits, making them safe for human use.</p> Conclusion <p>The effect of the laser wavelength on the properties of the prepared diamond nanoparticles was observed, as well as on their antibacterial performance. The particles prepared at 532 nm were shown to have improved efficacy and safety characteristics, suggesting their potential use as antibacterial agents in dental applications.</p>

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A comparative analysis of diamond nanoparticles prepared by pulsed laser for antibacterial application against Streptococcus mutans

  • 期刊论文

  • 发表日期：

    2025年9月10日

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  • Fattin A. Fadhil,
  • Ahlam Taha Mohammed,
  • Azhar M. Haleem,
  • Abdulrahman Khalaf Ali

摘要

Background

Laser technologies have led to the development of nanomaterials, which, in turn, has opened new horizons in preventive dentistry applications, especially in combating bacteria that cause tooth decay. Diamond nanoparticles were chosen and found to be promising materials due to their unique physical and biological properties.

Objectives

This study aims to evaluate the laser wavelength (1064 nm vs. 532 nm) on the synthesis, characterization, and antibacterial effectiveness of DNPs against Streptococcus mutans and its effect on the properties and behavior of prepared diamond nanoparticles, their characterization and effectiveness against bacteria causing dental caries.

Materials and methods

Diamond nanoparticles were synthesized using the laser ablation in liquid (PLAL) technique using an Nd:YAG laser at two different wavelengths. The optical and structural properties of the prepared particles were analyzed using UV–Vis absorption spectroscopy, zeta potential measurement, X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM). The antibacterial activity against (S. mutans) and cytotoxicity was evaluated to ensure their safety for biouse was also tested.

Results

The particles prepared at 532 nm showed a blue shift in the absorption spectrum, indicating high stability in the colloidal suspension with a surface potential of −30.1 mV. XRD patterns revealed the presence of a crystalline diamond structure, particularly at the (111) and (220) planes. TEM and FESEM images showed that the particles prepared at 532 nm were smaller (3–45 nm) and, compared to the particles prepared at 1064 nm, were found to be more homogeneous, less agglomerated, and more homogeneous. The results also demonstrated that their toxicity was within acceptable limits, making them safe for human use.

Conclusion

The effect of the laser wavelength on the properties of the prepared diamond nanoparticles was observed, as well as on their antibacterial performance. The particles prepared at 532 nm were shown to have improved efficacy and safety characteristics, suggesting their potential use as antibacterial agents in dental applications.