Preconceptional care for prevention of hyperglycaemia in pregnancy and future noncommunicable diseases: DIPSI position statement 2026 aligned with FIGO and FOGSI
摘要
Hyperglycaemia in pregnancy (HIP), encompassing gestational diabetes mellitus (GDM) and diabetes in pregnancy (DIP), is increasingly recognized as an early marker in the life-course trajectory of noncommunicable diseases (NCDs). In developing countries such as India, a substantial proportion of women enter pregnancy with preexisting metabolic risk factors, limiting the preventive impact of antenatal-only screening strategies.
ObjectivesTo propose an India-specific framework for prevention of HIP through preconceptional metabolic optimization, aligned with the life-course approach endorsed by the International Federation of Gynaecology and Obstetrics (FIGO) and supported by FOGSI.
MethodsThis position statement synthesizes global evidence, epidemiological data and DIPSI experience to develop a pragmatic framework for preconceptional screening, risk stratification and intervention using both globally accepted diagnostic standards and context-specific approaches.
ResultsDIPSI recommends opportunistic preconceptional screening using standard diagnostic criteria for nonpregnant adults, including fasting 75 g OGTT and HbA1c, while permitting nonfasting glucose testing for initial risk identification in resource-constrained settings. Women are stratified into normoglycaemia, prediabetes and pregestational diabetes. Core interventions include lifestyle modification, micronutrient optimization, pharmacological management where indicated and family- and couple-centric counselling. Selective use of self-monitoring and continuous glucose monitoring is recommended. Integration into existing health systems with differentiated urban and rural strategies is emphasized.
ConclusionPreconceptional care represents the earliest, most effective and most equitable opportunity to prevent GDM and future NCDs. A simplified, scalable, woman- and family-centred approach can interrupt the intergenerational cycle of metabolic disease.