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Background <p>Morbid obesity in young adults is a rising health challenge globally and in India, increasingly associated with early cardiometabolic complications.</p> Objective <p>This study aimed to evaluate the clinical burden and associated comorbidities among morbidly obese individuals aged 45&#xa0;years or younger.</p> Methods <p>A retrospective observational study in morbidly obese young patients was conducted at the National Heart Institute, New Delhi. Outpatient Department records from 2016 to 15th March 2025 were analyzed. Seventy-eight patients aged 45&#xa0;years and below with a body mass index (BMI) ≥ 35&#xa0;kg/m2 were included. Data collected included demographics, comorbidities, metabolic parameters, lifestyle risk factors, and family history.</p> Results <p>The mean age of patients was 34.65 ± 6.76&#xa0;years, with an average BMI of 39.46 ± 9.04&#xa0;kg/m2. Among them, 74.25% had at least one comorbidity. Common comorbidities included known type 2 diabetes (58.6%), hypertension (56.89%), dyslipidemia (31.03%), and hypothyroidism (17.24%). Coronary artery disease (CAD) was diagnosed in 8.62%, with ECG changes in 16.7%. Raised fasting blood sugar was observed in 28.2%, and ultrasound abnormalities (fatty liver/hepatomegaly) in 39.7%. Lifestyle-related risks included smoking and alcohol use (25.6%). Family history of diabetes or CAD was also found in a significant number. (30.8%).</p> Conclusion <p>This study underscores the significant clinical burden of morbid obesity in young adults, highlighting the role of metabolic aberrations, genetics, and lifestyle. Early identification of obesity in young people and counselling are vital to preventing long- term complications of obesity and its progression in young people.</p>

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Exploring the impact of morbid obesity on cardiovascular and metabolic parameters in young individuals

  • 期刊论文

  • 发表日期：

    2026年3月18日

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  • Akshita Iyer,
  • Vinod Sharma,
  • Shridhar Dwivedi

摘要

Background

Morbid obesity in young adults is a rising health challenge globally and in India, increasingly associated with early cardiometabolic complications.

Objective

This study aimed to evaluate the clinical burden and associated comorbidities among morbidly obese individuals aged 45 years or younger.

Methods

A retrospective observational study in morbidly obese young patients was conducted at the National Heart Institute, New Delhi. Outpatient Department records from 2016 to 15th March 2025 were analyzed. Seventy-eight patients aged 45 years and below with a body mass index (BMI) ≥ 35 kg/m2 were included. Data collected included demographics, comorbidities, metabolic parameters, lifestyle risk factors, and family history.

Results

The mean age of patients was 34.65 ± 6.76 years, with an average BMI of 39.46 ± 9.04 kg/m2. Among them, 74.25% had at least one comorbidity. Common comorbidities included known type 2 diabetes (58.6%), hypertension (56.89%), dyslipidemia (31.03%), and hypothyroidism (17.24%). Coronary artery disease (CAD) was diagnosed in 8.62%, with ECG changes in 16.7%. Raised fasting blood sugar was observed in 28.2%, and ultrasound abnormalities (fatty liver/hepatomegaly) in 39.7%. Lifestyle-related risks included smoking and alcohol use (25.6%). Family history of diabetes or CAD was also found in a significant number. (30.8%).

Conclusion

This study underscores the significant clinical burden of morbid obesity in young adults, highlighting the role of metabolic aberrations, genetics, and lifestyle. Early identification of obesity in young people and counselling are vital to preventing long- term complications of obesity and its progression in young people.