Scholarlink

Background <p>Septic patients with type 2 diabetes mellitus (DM) face increased mortality risks, necessitating accurate prognostic tools for patient management.</p> Objective <p>This study aimed to assess the association between the Braden score, a measure of skin pressure injury risk, and 28-day all-cause mortality in septic patients with type 2 DM.</p> Methods <p>A retrospective observational cohort study was conducted using the MIMIC-IV database, comprising adult ICU patients admitted between 2008 and 2019. Sepsis and septic shock diagnoses followed sepsis-3 criteria, with patient identification based on SQL methods. Multivariate Cox regression analysis was employed to evaluate the Braden score’s independent association with mortality, adjusting for demographic, clinical, and laboratory variables.</p> Results <p>Among the 7392 patients included, the mean age was 70.12&#xa0;years, with a mortality rate of 19.5%. The Braden score was significantly associated with 28-day all-cause mortality in both unadjusted and adjusted models. In the unadjusted model, each 1-point increase in Braden score was associated with a lower risk of mortality (HR = 0.88; 95% CI 0.78–0.98; <i>p</i> &lt; 0.001). In the fully adjusted model 3, the Braden score demonstrated a significant association with 28-day all-cause mortality (HR = 0.94; 95% CI 0.83–0.99; <i>p</i> &lt; 0.001). The ROC curve analysis for the Braden score predicting mortality yielded an AUC of 0.78 (95% CI 0.69–0.88).</p> Conclusion <p>The Braden score emerged as an independent predictor of 28-day all-cause mortality in septic patients with type 2 DM, with higher scores indicating lower mortality risk.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Braden score is independently associated with mortality in septic patients with type 2 diabetes

  • 期刊论文

  • 发表日期：

    2026年1月13日

查看全文
  • Ping Song,
  • Yuan Zeng

摘要

Background

Septic patients with type 2 diabetes mellitus (DM) face increased mortality risks, necessitating accurate prognostic tools for patient management.

Objective

This study aimed to assess the association between the Braden score, a measure of skin pressure injury risk, and 28-day all-cause mortality in septic patients with type 2 DM.

Methods

A retrospective observational cohort study was conducted using the MIMIC-IV database, comprising adult ICU patients admitted between 2008 and 2019. Sepsis and septic shock diagnoses followed sepsis-3 criteria, with patient identification based on SQL methods. Multivariate Cox regression analysis was employed to evaluate the Braden score’s independent association with mortality, adjusting for demographic, clinical, and laboratory variables.

Results

Among the 7392 patients included, the mean age was 70.12 years, with a mortality rate of 19.5%. The Braden score was significantly associated with 28-day all-cause mortality in both unadjusted and adjusted models. In the unadjusted model, each 1-point increase in Braden score was associated with a lower risk of mortality (HR = 0.88; 95% CI 0.78–0.98; p < 0.001). In the fully adjusted model 3, the Braden score demonstrated a significant association with 28-day all-cause mortality (HR = 0.94; 95% CI 0.83–0.99; p < 0.001). The ROC curve analysis for the Braden score predicting mortality yielded an AUC of 0.78 (95% CI 0.69–0.88).

Conclusion

The Braden score emerged as an independent predictor of 28-day all-cause mortality in septic patients with type 2 DM, with higher scores indicating lower mortality risk.