<p>Thin-walled cold-formed steel (CFS) members are susceptible to the presence of imperfections due to improper handling during transportation and fabrication stages. Being thin sections, these members tend to fail in instabilities such as local, distortional, lateral-torsional or a combination of multiple buckling modes. The CFS members are also vulnerable for failure in the event of a fire due to their high section factor. This study aims particularly on flexural members at elevated temperatures (20–800&#xa0;°C) under local-distortional coupled buckling mode involved, having varied imperfection magnitudes. A numerical finite element (FE) model is developed and verified using previous studies and is further utilized for the parametric study. First, the finite strip-based analysis is performed to comprehend the possible modes of buckling involved for the particular geometry of the member. Then, the selected geometric profiles are utilized in the thermo-mechanical nonlinear analysis using finite element-based approach. Several combinations of imperfection are considered in this research to study the impact of imperfection magnitudes on the flexural member capacity exposed to fire. Existing direct strength method (DSM)-based equations have been checked for the member strength prediction, and new modified equations are proposed in this study. A thorough statistical and reliability-based investigation is conducted in order to check the proposed modified equations for accuracy and reliability in member strength prediction. The modified proposal in this research is found to predict the strength with more accuracy and reliability than the existing method.</p>