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<p>This retrospective study compared the rate of feed intolerance in preterm neonates delivered at ≤ 30 weeks gestation who received pasteurised donor human milk (<i>n</i> = 83) versus preterm formula (<i>n</i> = 41) to meet the deficits in available volumes of mother’s own milk in the first 2 weeks of life. Feed intolerance was not higher in neonates who received preterm formula than those who received pasteurized donor human milk (24.4% vs 20%; OR (95% CI) 0.79 (0.30, 2.19) <i>P</i> = 0.619]. Rates of necrotizing enterocolitis, culture positive sepsis and mortality were not significantly different in the two groups. The preterm formula group gained birth weight earlier, although the time needed to attain full feeds was similar in both groups.</p>

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Feed Intolerance With Short Term Use of Commercial Pasteurized Donor Human Milk Versus Preterm Formula in Addition to Mother’s Milk: A Retrospective Analytical Study

  • 期刊论文

  • 发表日期：

    2025年1月3日

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  • Rajesh Raghavan Nalini,
  • Mohamed Muneer Varikkottil,
  • Femitha Pournami,
  • Ajai Kumar Prithvi,
  • Naveen Jain

摘要

This retrospective study compared the rate of feed intolerance in preterm neonates delivered at ≤ 30 weeks gestation who received pasteurised donor human milk (n = 83) versus preterm formula (n = 41) to meet the deficits in available volumes of mother’s own milk in the first 2 weeks of life. Feed intolerance was not higher in neonates who received preterm formula than those who received pasteurized donor human milk (24.4% vs 20%; OR (95% CI) 0.79 (0.30, 2.19) P = 0.619]. Rates of necrotizing enterocolitis, culture positive sepsis and mortality were not significantly different in the two groups. The preterm formula group gained birth weight earlier, although the time needed to attain full feeds was similar in both groups.