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<p>The national guidelines for evaluation of aggressive retinopathy of prematurity (AROP) in preterm neonates recommend the first examination at 2–3&#xa0;weeks of age. This retrospective study investigated the yield of AROP checks performed at 3&#xa0;weeks of postnatal age in neonates delivered between 23 and 28&#xa0;weeks of gestation. Of the 260 eye examinations done at 3&#xa0;weeks of age, none resulted in need for therapy for ROP over the ensuing week. Feed intolerance and cardiorespiratory events were noted after/during the AROP screening in one-third of the neonates. The median (Q1, Q3) time gap between the first AROP screening and any need for therapy was 8 (5, 9) weeks. This suggests that more evidence from prospective studies is required to corroborate the existing national guidelines for early retinal examinations.</p>

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Yield of Early Examination for Aggressive Retinopathy of Prematurity: A Retrospective Study

  • 期刊论文

  • 发表日期：

    2025年11月20日

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  • Mohamed Muneer Varikkottil,
  • Zubair Ahmad Bhat,
  • Femitha Pournami,
  • Arif Abdulsalam Kolisambeevi,
  • Naveen Jain

摘要

The national guidelines for evaluation of aggressive retinopathy of prematurity (AROP) in preterm neonates recommend the first examination at 2–3 weeks of age. This retrospective study investigated the yield of AROP checks performed at 3 weeks of postnatal age in neonates delivered between 23 and 28 weeks of gestation. Of the 260 eye examinations done at 3 weeks of age, none resulted in need for therapy for ROP over the ensuing week. Feed intolerance and cardiorespiratory events were noted after/during the AROP screening in one-third of the neonates. The median (Q1, Q3) time gap between the first AROP screening and any need for therapy was 8 (5, 9) weeks. This suggests that more evidence from prospective studies is required to corroborate the existing national guidelines for early retinal examinations.