<p>In candidates for hepatectomy, different techniques to induce liver hypertrophy and modulate the future liver remnant are available. However, their use in specific clinical scenarios is highly heterogeneous and there is no consensus about minimal safety standards needed to incorporate these strategies into routine clinical practice. The aim of this position paper was to summarize newly available evidence in the field and compare medical practice among different hepatobiliary surgical units to evaluate the transformative potential of liver hypertrophy techniques in surgical oncology. This paper sets the stage for a future structured consensus on the application of liver hypertrophy techniques before hepatectomy.</p>

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Liver hypertrophy techniques: a position paper from the Italian Group of Regenerative and Occlusive Worldwide-used techniques of hepatic Hypertrophy (I GROWtoH)

  • Matteo Serenari,
  • Francesca Ratti,
  • Mohammed Abu Hilal,
  • Francesco Ardito,
  • Giammauro Berardi,
  • Ugo Boggi,
  • Alberta Cappelli,
  • Matteo Cescon,
  • Umberto Cillo,
  • Alessandro Cucchetti,
  • Luciano De Carlis,
  • Francesco De Cobelli,
  • Fabrizio Di Benedetto,
  • Giorgio Ercolani,
  • Giuseppe Maria Ettorre,
  • Massimo Fedi,
  • Alessandro Ferrero,
  • Felice Giuliante,
  • Gian Luca Grazi,
  • Enrico Gringeri,
  • Salvatore Gruttadauria,
  • Francesco Izzo,
  • Marcello Maestri,
  • Paolo Magistri,
  • Marco Massani,
  • Vincenzo Mazzaferro,
  • Riccardo Memeo,
  • Federico Mocchegiani,
  • Cristina Mosconi,
  • Damiano Patrono,
  • Matteo Ravaioli,
  • Fabrizio Romano,
  • Gianluca Rompianesi,
  • Nadia Russolillo,
  • Andrea Ruzzenente,
  • Carlo Sposito,
  • Roberto Troisi,
  • Giovanni Vennarecci,
  • Luca Viganò,
  • Marco Vivarelli,
  • Giacomo Zanus,
  • Pedro M. Baptista,
  • Karl Oldhafer,
  • Erik Schadde,
  • Luca Aldrighetti,
  • Elio Jovine

摘要

In candidates for hepatectomy, different techniques to induce liver hypertrophy and modulate the future liver remnant are available. However, their use in specific clinical scenarios is highly heterogeneous and there is no consensus about minimal safety standards needed to incorporate these strategies into routine clinical practice. The aim of this position paper was to summarize newly available evidence in the field and compare medical practice among different hepatobiliary surgical units to evaluate the transformative potential of liver hypertrophy techniques in surgical oncology. This paper sets the stage for a future structured consensus on the application of liver hypertrophy techniques before hepatectomy.