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Objective <p>To evaluate the performance of WHO and INTERGROWTH-21 (IG-21) fetal growth charts in the Indian population.</p> Methods <p>A total of 250 pregnant women were recruited in this prospective observational pilot study&#xa0;carried out&#xa0;at a tertiary care hospital,&#xa0;New Delhi, India. Women underwent ultrasound scans for fetal biometry twice during their pregnancy, at 24–26&#xa0;weeks and 34–36&#xa0;weeks gestation. Measured values were plotted on WHO and INTERGROWTH-21 fetal growth charts. The 10th, 50th, and 90th centiles of fetal biometry were calculated for the study population, and prepared study charts were compared to the two growth charts for respective centiles.</p> Results <p>There was an agreement for both WHO and IG-21 charts with all the centiles of study charts for HC in both the 2nd and 3rd trimesters. However, the WHO chart had an agreement with the study charts for FL at all centiles but IG-21 underestimated FL in both trimesters. WHO chart was in agreement with the study population for BPD at 10th and 50th centiles only and IG-21 overestimated BPD at all centiles in both trimesters. For AC, both WHO and IG-21 charts have an agreement with study charts at the 10th and 50th centile at all gestations. However, for the 90th centile, IG-21 underestimates AC and the WHO chart agrees with the study population in 2nd trimester only. For EFW in the 2nd trimester, both WHO and IG-21 charts agreed to the study charts at all centiles but in the 3rd trimester WHO chart overestimates and IG-21 underestimates the study population for the 10th and 50th centiles.</p> Conclusion <p>According to this pilot study, neither WHO nor IG-21 charts are a good fit for the Indian population, and locally developed fetal growth charts are needed.</p>

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Evaluation of WHO and INTERGROWTH-21 Fetal Growth Charts in Indian Population

  • 期刊论文

  • 发表日期：

    2025年10月6日

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  • Gupta Akanksha,
  • Dadhwal Vatsla,
  • Vidushi Kulshrestha,
  • Vanamail Perumal,
  • Sachdeva Anu,
  • Kumar Sunesh

摘要

Objective

To evaluate the performance of WHO and INTERGROWTH-21 (IG-21) fetal growth charts in the Indian population.

Methods

A total of 250 pregnant women were recruited in this prospective observational pilot study carried out at a tertiary care hospital, New Delhi, India. Women underwent ultrasound scans for fetal biometry twice during their pregnancy, at 24–26 weeks and 34–36 weeks gestation. Measured values were plotted on WHO and INTERGROWTH-21 fetal growth charts. The 10th, 50th, and 90th centiles of fetal biometry were calculated for the study population, and prepared study charts were compared to the two growth charts for respective centiles.

Results

There was an agreement for both WHO and IG-21 charts with all the centiles of study charts for HC in both the 2nd and 3rd trimesters. However, the WHO chart had an agreement with the study charts for FL at all centiles but IG-21 underestimated FL in both trimesters. WHO chart was in agreement with the study population for BPD at 10th and 50th centiles only and IG-21 overestimated BPD at all centiles in both trimesters. For AC, both WHO and IG-21 charts have an agreement with study charts at the 10th and 50th centile at all gestations. However, for the 90th centile, IG-21 underestimates AC and the WHO chart agrees with the study population in 2nd trimester only. For EFW in the 2nd trimester, both WHO and IG-21 charts agreed to the study charts at all centiles but in the 3rd trimester WHO chart overestimates and IG-21 underestimates the study population for the 10th and 50th centiles.

Conclusion

According to this pilot study, neither WHO nor IG-21 charts are a good fit for the Indian population, and locally developed fetal growth charts are needed.