Evolving Experience with Minimally Invasive Rectal Cancer Surgery: A Nine-Year Single-Centre Propensity-Matched Analysis from South India
摘要
Robotic surgery has rapidly gained acceptance in rectal cancer owing to improved visualization and precision. This study compared perioperative and short-term oncologic outcomes of laparoscopic versus robotic rectal resections at a single tertiary oncology centre.
MethodsAll patients undergoing curative rectal cancer resection between 2016 and 2022 (laparoscopic) and 2022–2025 (robotic) were retrospectively reviewed. Propensity score matching (1:1) was performed based on age, neoadjuvant chemoradiotherapy (NACRT), pathological stage, tumour grade, circumferential resection margin (CRM) and preoperative CEA, yielding 35 matched cases per group. Balance between groups before and after matching was assessed using standardized mean differences (SMD), with an SMD < 0.1 considered indicative of adequate covariate balance. Perioperative parameters, complications, and disease-free survival (DFS) were compared. Kaplan–Meier analysis was used; projected 36-month DFS was reported where robotic follow-up was < 36 months.
ResultsSeventy matched patients were analysed. Baseline characteristics, including CRM status and lymph node harvest, were comparable. Estimated blood loss was significantly lower in the robotic group (82.6 ± 22.3 ml vs. 129.4 ± 48.6 ml; p < 0.001). Operative duration was longer for robotic surgery (138.4 ± 21.2 min vs. 99.0 ± 9.1 min; p < 0.001). Postoperative morbidity, including ileus, urinary retention, and stoma-related complications, did not differ significantly. Observed 24-month DFS was numerically higher in the robotic group (81% vs. 73.5%). Projected 36-month DFS showed no statistically significant difference (p = 0.591).
ConclusionRobotic rectal resection offers reduced intraoperative blood loss with comparable postoperative morbidity and short-term oncologic outcomes to laparoscopy. Longer follow-up is needed to validate survival outcomes.