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<p>Bone is a common site for metastasis from various malignancies and is considered a poor prognostic indicator for both life expectancy and quality of life. Skeletal metastases lead to severe pain and pathological fractures, significantly impairing patients' daily functioning and well-being. Effective management of impending and pathological fractures is crucial in improving these patients' quality of life.</p><p>To evaluate the quality of life in patients with metastatic bone disease who underwent surgical treatment for impending and pathological fractures of the lower limb at a tertiary care hospital.</p><p>This retrospective observational study included patients who underwent surgical intervention for impending and pathological fractures of the lower limb due to metastatic bone disease. Functional outcomes were assessed using the Hindi-translated Indian version of the Toronto Extremity Salvage Score (TESS) for the lower limb.</p><p>A total of 22 patients were included, with a mean age of 50&#xa0;years (SD 17.9). The average TESS score for all patients was 48.8 (SD 20.02). The mean follow-up period was 15&#xa0;months (range 3–56&#xa0;months). A statistically significant difference in TESS scores was observed when age was considered as a variable (p &lt; 0.05), indicating an age-related impact on functional outcomes.</p><p>Prophylactic and therapeutic fixation of metastatic fractures significantly improves the quality of life in patients with metastatic bone disease. The use of the Indian version of the TESS questionnaire provided valuable insights into functional outcomes and quality of life in the Indian population.</p>

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Impact of Surgical Fixation on Quality of Life in Patients with Metastatic Bone Disease: A Retrospective Analysis

  • 期刊论文

  • 发表日期：

    2025年9月24日

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  • Vikas Maheshwari,
  • Mohit Dhingra

摘要

Bone is a common site for metastasis from various malignancies and is considered a poor prognostic indicator for both life expectancy and quality of life. Skeletal metastases lead to severe pain and pathological fractures, significantly impairing patients' daily functioning and well-being. Effective management of impending and pathological fractures is crucial in improving these patients' quality of life.

To evaluate the quality of life in patients with metastatic bone disease who underwent surgical treatment for impending and pathological fractures of the lower limb at a tertiary care hospital.

This retrospective observational study included patients who underwent surgical intervention for impending and pathological fractures of the lower limb due to metastatic bone disease. Functional outcomes were assessed using the Hindi-translated Indian version of the Toronto Extremity Salvage Score (TESS) for the lower limb.

A total of 22 patients were included, with a mean age of 50 years (SD 17.9). The average TESS score for all patients was 48.8 (SD 20.02). The mean follow-up period was 15 months (range 3–56 months). A statistically significant difference in TESS scores was observed when age was considered as a variable (p < 0.05), indicating an age-related impact on functional outcomes.

Prophylactic and therapeutic fixation of metastatic fractures significantly improves the quality of life in patients with metastatic bone disease. The use of the Indian version of the TESS questionnaire provided valuable insights into functional outcomes and quality of life in the Indian population.