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<p>The American College of Radiology (ACR) created the Breast Imaging Reporting and Data System, or BI-RADS, to standardize the way radiologists report mammography, ultrasound, and MRI findings.&#xa0;This study aimed to compare the diagnostic accuracy of combined mammography and sonography with that of mammography alone in differentiating malignant from benign breast masses. This 3-year, hospital-based cross-sectional study included female patients presenting with breast lumps. Diagnostic accuracy metrics, including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy, were calculated with histopathology as the gold standard. This study evaluated 590 female patients with breast lumps (mean age 46.3&#xa0;years), identifying 330 benign and 260 malignant cases. Fibroadenoma and invasive ductal carcinoma were the most common diagnoses. Patient age and body mass index (BMI) were significantly correlated with diagnosis, with an increased incidence of malignancy in the older and higher BMI groups, unlike fertility status; and, crucially, combining mammography with ultrasonography significantly enhanced breast lesion detection. This combined approach increased the sensitivity from 94.62% to 99.23% and the specificity from 86.67% to 90.91%. Consequently, both the PPV (84.83% to 89.58%) and NPV (95.33% to 99.34%) improved, resulting in an overall increase in diagnostic accuracy from 90.17% to 94.58%. This study revealed that combining mammography and sonography significantly improves the diagnostic accuracy for palpable breast masses, especially in differentiating between benign and malignant lesions. Integrating both imaging techniques into standard practice will lead to early diagnosis of malignant lesions and help avoid unnecessary biopsies for benign lesions.</p>

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Diagnostic Accuracy of the BI-RADS, Using Both Mammograms and Sonograms, in Distinguishing Between Benign and Malignant Breast Masses

  • 期刊论文

  • 发表日期：

    2025年10月8日

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  • Neha Nupur,
  • Madhusmita Mohanty,
  • Katyayani Panda,
  • Nihar Ranjan Mohanty,
  • Sashibhusan Dash

摘要

The American College of Radiology (ACR) created the Breast Imaging Reporting and Data System, or BI-RADS, to standardize the way radiologists report mammography, ultrasound, and MRI findings. This study aimed to compare the diagnostic accuracy of combined mammography and sonography with that of mammography alone in differentiating malignant from benign breast masses. This 3-year, hospital-based cross-sectional study included female patients presenting with breast lumps. Diagnostic accuracy metrics, including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy, were calculated with histopathology as the gold standard. This study evaluated 590 female patients with breast lumps (mean age 46.3 years), identifying 330 benign and 260 malignant cases. Fibroadenoma and invasive ductal carcinoma were the most common diagnoses. Patient age and body mass index (BMI) were significantly correlated with diagnosis, with an increased incidence of malignancy in the older and higher BMI groups, unlike fertility status; and, crucially, combining mammography with ultrasonography significantly enhanced breast lesion detection. This combined approach increased the sensitivity from 94.62% to 99.23% and the specificity from 86.67% to 90.91%. Consequently, both the PPV (84.83% to 89.58%) and NPV (95.33% to 99.34%) improved, resulting in an overall increase in diagnostic accuracy from 90.17% to 94.58%. This study revealed that combining mammography and sonography significantly improves the diagnostic accuracy for palpable breast masses, especially in differentiating between benign and malignant lesions. Integrating both imaging techniques into standard practice will lead to early diagnosis of malignant lesions and help avoid unnecessary biopsies for benign lesions.