<p>Established in 2010, the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) Core Registry has systematically captured data from in-hospital and clinic-based medical toxicology physician consultations across the United States (US) and internationally. The ToxIC Core Registry contains deidentified patient data, including patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality outcomes. This fifteenth annual report provides data from 8,868 patients entered into the Core Registry in 2024, bringing the total number of cases to 111,276 between 2010 and 2024. These cases were submitted by 41 participating sites encompassing 67 distinct hospitals over 23 US states and 3 international countries. In 2024, ethanol was the most commonly reported exposure agent class (17.8%), followed by opioids (15.8%), non-opioid analgesics (10.5%), and sympathomimetic agents (7.6%). A total of 107 fatalities were reported, corresponding to a case fatality rate of 1.2%. Additional descriptive analyses in this annual report were conducted to describe trends for opioid and psychoactive exposures between 2010 and 2024.</p>

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The Toxicology Investigators Consortium 2024 Annual Report

  • Kim Aldy,
  • Shao Li,
  • Mari Costantini,
  • Alyssa Falise,
  • Rachel Culbreth,
  • Paul M. Wax,
  • Jeffery Brent,
  • Michael Abesamis,
  • Faiz Ahmed,
  • Salman Ahsan,
  • Peter Akpunonu,
  • Adam Algren,
  • Afra Alsuwaidi,
  • Jacob Altholz,
  • Alexandra Amaducci,
  • Kassaundra Amann,
  • John Archer,
  • Alexia Armenta,
  • Yaqdhan Al Atbil,
  • Sukhshant Atti,
  • Megan Audette,
  • Robert Avera,
  • Kavita Babu,
  • Klara De Baerdemaeker,
  • Kevin Baumgartner,
  • Gillian Beauchamp,
  • Vik Bebarta,
  • Melisa Lai Becker,
  • Michael-John Beltejar,
  • Laura Beneke,
  • Sarah Berg,
  • Michael Beuhler,
  • Steven Bird,
  • Blake Blakely,
  • Eric Bloom,
  • Matthew Blundell,
  • Molly Boyd-Smith,
  • Evan Bradley,
  • Nicklaus Brandehoff,
  • Daniel Brooks,
  • Connor Brown,
  • Jennie Buchanan,
  • Cameron Burke,
  • Sarah Burke,
  • Michele Burns,
  • Diane Calello,
  • Vincent Calleo,
  • Alexa Camarena-Michel,
  • Joshua Canning,
  • Dazhe Cao,
  • Jennifer Carey,
  • Joseph Carpenter,
  • Stephanie Carreiro,
  • David Carroll,
  • Emma Cassidy,
  • Rachel Castelli,
  • Edward Cetaruk,
  • Neeraj Chabra,
  • Nathan Charlton,
  • Michael Chary,
  • Kathleen Chen,
  • Richard Chen,
  • Samy Chettat,
  • Richard Church,
  • Al Conicella,
  • Mathew Cook,
  • Matthew Correia,
  • Christopher Counts,
  • Colleen Cowdery,
  • Robert Cox,
  • Mitchell D’Aloia,
  • Paul Dargan,
  • John Delbianco,
  • Aaron Deutsch,
  • Frank Dicker,
  • Bram Dolcourt,
  • Cullan Donnelly,
  • Kaila Druetto,
  • Natalie Ebeling-Koning,
  • Bernard Eisenga,
  • Jason Elzinga,
  • Andrew Farkas,
  • Henry Farrar,
  • Chris Feng,
  • Sing Feng,
  • Derek Fikse,
  • Ari Filip,
  • Allison Font,
  • Carolyn Fox,
  • Abby Frank,
  • Caleb Fredrickson,
  • Aaron Frey,
  • Blake Froberg,
  • Emma Furlano,
  • Samantha Gaetani,
  • Kira Galeano,
  • Hayley Gartner,
  • Austin Gay,
  • Melissa Gittinger,
  • Timlin Glaser,
  • David Goldberger,
  • Kimberlie Graeme,
  • Powell Graham,
  • Spencer Greene,
  • Howard Greller,
  • Veronica Groff,
  • Enoila Gros,
  • Stacey Hail,
  • Christy Hallett,
  • Laurie Halmo,
  • Alexandra Hamelin,
  • Amy Harris,
  • Denzil Harris,
  • Riley Hartmann,
  • Benjamin Hatten,
  • Kennon Heard,
  • Carleigh Hebbard,
  • Will Heise,
  • Rob Hendrickson,
  • Reynaldo Hernandez,
  • Jacqui Hiob,
  • Ruby Hoang,
  • Robert Hoffman,
  • Christopher Holstege,
  • Jason Hoppe,
  • Keahi Horowitz,
  • Zane Horowitz,
  • Christopher Hoyte,
  • Adrienne Hughes,
  • Laura Hunter,
  • Katherine Hurlbut,
  • Nick Husak,
  • Damilola Idowu,
  • Ivan Ivanov,
  • Janetta Iwanicki,
  • Sundip Jagpal,
  • Laura James,
  • Linda Johnson,
  • Michael Johnson,
  • Chase Jones,
  • Bryan Judge,
  • Min Kang,
  • Louise Kao,
  • Kenneth Katz,
  • Michael Keenan,
  • Chris Kennedy,
  • Abigail Kerns,
  • Michael Khoury,
  • Emily Kiernan,
  • Kathryn Kimpel,
  • Andrew King,
  • Clayton Kirk,
  • Kurt Kleinschmidt,
  • Matthew Kolbeck,
  • Andrew Koons,
  • Michael Kosnett,
  • Michael Kowalski,
  • James Krueger,
  • Jessica Krueger,
  • Shana Kusin,
  • Jeffrey Lai,
  • Matthew Lambrych,
  • Mary Lark,
  • Becky Latch,
  • Dan Laub,
  • Eric Lavonas,
  • Duaa Al Lawati,
  • Alexander Lazar,
  • Jacob Lebin,
  • Michael Levine,
  • Carl Levy,
  • Brian Lewis,
  • Erica Liebelt,
  • Rafael Lima,
  • David Liss,
  • Heather Long,
  • Annette Lopez,
  • Michael Lynch,
  • Forrest Mahoney,
  • Greg Makar,
  • Michael Marlin,
  • Brandon Marshall,
  • Stacy Marshall,
  • Kelsey Martin,
  • Danae Massengill,
  • Nik Matsler,
  • Sean McCann,
  • Conner McDonald,
  • Joshua McFalls,
  • Christopher Meaden,
  • Kevan Meadors,
  • Timothy Meehan,
  • Avery Michienzi,
  • Michelle Mieger,
  • Christopher Mitchell,
  • Nadia Mohammad,
  • Andrew Monte,
  • Elizabeth Moore,
  • Pamela Moore,
  • Anita Mudan,
  • Michael Mullins,
  • Karen Muschler,
  • Agnesa Mustafa,
  • Nicholas Nacca,
  • Kristine Nanagas,
  • Lewis Nelson,
  • Hoan Nguyen,
  • Kim-Long Nguyen,
  • Andrea Nillas,
  • Supa Niruntarai,
  • Sandra Nixon,
  • Hannah Norton,
  • Katherine O’Donnell,
  • Nneka Ogbutor,
  • Jonathan de Olano,
  • Simon Ostrowski,
  • Rittirak Othong,
  • Jenna Otter,
  • Daniel Overbeek,
  • Serah Oyewole,
  • Mehruba Parris,
  • Todd Phillips,
  • Anthony Pizon,
  • John Rague,
  • Ravikar Ralph,
  • Aaron Ralston,
  • Shelby Randall,
  • Rama Rao,
  • Shahanaz Rashid,
  • Tony Rianprakaisang,
  • Morgan Riga,
  • Marc Rigatti,
  • Bradley Riley,
  • Daniel Rivera,
  • Lynne Rosenberg,
  • Brett Roth,
  • Adam Rowden,
  • Anne-Michlle Ruha,
  • William Rushton,
  • Steven Salhanick,
  • Cynthia Santos,
  • Nishita Saraiya,
  • Zariad Saran,
  • Alkeem Savage,
  • Matthew Scanlon,
  • Scott Schmalzried,
  • Brett Schuchardt,
  • Evan Schwarz,
  • Anthony Scoccimarro,
  • Elizabeth Shanahan,
  • Kapil Sharma,
  • Andrew Sheen,
  • Sophia Sheikh,
  • Tiffany Sheng,
  • Edward Shin,
  • Joshua Shulman,
  • Alex Sidlak,
  • Michael Simpson,
  • Serge Emile Simpson,
  • Miya Smith,
  • Jerry Snow,
  • Anthony Spadaro,
  • Hannah Spungen,
  • Meghan Spyres,
  • Alaina Steck,
  • Jennifer Stephani,
  • Darien Stratton,
  • Fermin Suarez,
  • Lachie Sund,
  • Ryan Surmaitis,
  • Sammy Taha,
  • Katherine Tang,
  • Neel Tarikeri,
  • Courtney Temple,
  • John Thompson,
  • Trevonne Thompson,
  • Christian Thornton,
  • Christopher Threapleton,
  • Daniel Tirado,
  • Michael Toce,
  • Laura Tormoehlen,
  • Cassie Trammel,
  • William Trautman,
  • Supatpinee Trensawang,
  • Andrew Troger,
  • Alicia Tudor,
  • Merritt Tuttle,
  • David Vearrier,
  • Steven Walsh,
  • Herbert Wan,
  • Sam Wang,
  • Yu-Chi Wang,
  • George Warpinski,
  • Marcus Warriner,
  • Timothy Weigand,
  • Ben Weigel,
  • Marey Wermuth,
  • Brian Wiener,
  • Adrian Williamson,
  • Tyler Willing,
  • Bryan Wilson,
  • Jessica Winkels,
  • Brian Wolk,
  • David Wood,
  • Mark Yarema,
  • Alison Yarp,
  • Luke Yip,
  • Amy Young,
  • Conor Young,
  • Roland Zemla,
  • Anna Zmuda,
  • Josue Zozaya,
  • Matthew Zuckerman,
  • Kara Zweerink

摘要

Established in 2010, the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) Core Registry has systematically captured data from in-hospital and clinic-based medical toxicology physician consultations across the United States (US) and internationally. The ToxIC Core Registry contains deidentified patient data, including patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality outcomes. This fifteenth annual report provides data from 8,868 patients entered into the Core Registry in 2024, bringing the total number of cases to 111,276 between 2010 and 2024. These cases were submitted by 41 participating sites encompassing 67 distinct hospitals over 23 US states and 3 international countries. In 2024, ethanol was the most commonly reported exposure agent class (17.8%), followed by opioids (15.8%), non-opioid analgesics (10.5%), and sympathomimetic agents (7.6%). A total of 107 fatalities were reported, corresponding to a case fatality rate of 1.2%. Additional descriptive analyses in this annual report were conducted to describe trends for opioid and psychoactive exposures between 2010 and 2024.