<p>We study a transmission problem of Neumann–Robin type involving a parameter <InlineEquation ID="IEq1"> <EquationSource Format="TEX">\(\alpha \)</EquationSource> <EquationSource Format="MATHML"><math> <mi>α</mi> </math></EquationSource> </InlineEquation> and perform an asymptotic analysis with respect to <InlineEquation ID="IEq2"> <EquationSource Format="TEX">\(\alpha \)</EquationSource> <EquationSource Format="MATHML"><math> <mi>α</mi> </math></EquationSource> </InlineEquation>. The limits <InlineEquation ID="IEq3"> <EquationSource Format="TEX">\(\alpha \rightarrow 0\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mi>α</mi> <mo stretchy="false">→</mo> <mn>0</mn> </mrow> </math></EquationSource> </InlineEquation> and <InlineEquation ID="IEq4"> <EquationSource Format="TEX">\(\alpha \rightarrow +\infty \)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mi>α</mi> <mo stretchy="false">→</mo> <mo>+</mo> <mi>∞</mi> </mrow> </math></EquationSource> </InlineEquation> correspond respectively to complete decoupling and full unification of the problem, and we obtain rates of convergence for both regimes. Biologically, the model describes two cells connected by a gap junction with permeability <InlineEquation ID="IEq5"> <EquationSource Format="TEX">\(\alpha \)</EquationSource> <EquationSource Format="MATHML"><math> <mi>α</mi> </math></EquationSource> </InlineEquation>: the case <InlineEquation ID="IEq6"> <EquationSource Format="TEX">\(\alpha \rightarrow 0\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mi>α</mi> <mo stretchy="false">→</mo> <mn>0</mn> </mrow> </math></EquationSource> </InlineEquation> corresponds to a situation where the gap junction is closed, leaving only tight junctions between the cells so that no substance exchange occurs, while <InlineEquation ID="IEq7"> <EquationSource Format="TEX">\(\alpha \rightarrow +\infty \)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mi>α</mi> <mo stretchy="false">→</mo> <mo>+</mo> <mi>∞</mi> </mrow> </math></EquationSource> </InlineEquation> corresponds to a situation that can be interpreted as the cells forming a single structure. We also clarify the relationship between the asymptotic analysis with respect to the parameter <InlineEquation ID="IEq8"> <EquationSource Format="TEX">\(\alpha \)</EquationSource> <EquationSource Format="MATHML"><math> <mi>α</mi> </math></EquationSource> </InlineEquation> and the asymptotics of the system in connection with the convergence of convex functionals known as Mosco convergence. Finally, we consider time-dependent permeability and analyze the case where <InlineEquation ID="IEq9"> <EquationSource Format="TEX">\(\alpha \)</EquationSource> <EquationSource Format="MATHML"><math> <mi>α</mi> </math></EquationSource> </InlineEquation> blows up in finite time. Under suitable regularity assumptions, we show that the solution can be extended beyond the blow-up time, remaining in the single structure regime.</p>

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Asymptotic analysis of transmission problems with parameter-dependent Robin conditions

  • Takeshi Fukao

摘要

We study a transmission problem of Neumann–Robin type involving a parameter \(\alpha \) α and perform an asymptotic analysis with respect to \(\alpha \) α . The limits \(\alpha \rightarrow 0\) α 0 and \(\alpha \rightarrow +\infty \) α + correspond respectively to complete decoupling and full unification of the problem, and we obtain rates of convergence for both regimes. Biologically, the model describes two cells connected by a gap junction with permeability \(\alpha \) α : the case \(\alpha \rightarrow 0\) α 0 corresponds to a situation where the gap junction is closed, leaving only tight junctions between the cells so that no substance exchange occurs, while \(\alpha \rightarrow +\infty \) α + corresponds to a situation that can be interpreted as the cells forming a single structure. We also clarify the relationship between the asymptotic analysis with respect to the parameter \(\alpha \) α and the asymptotics of the system in connection with the convergence of convex functionals known as Mosco convergence. Finally, we consider time-dependent permeability and analyze the case where \(\alpha \) α blows up in finite time. Under suitable regularity assumptions, we show that the solution can be extended beyond the blow-up time, remaining in the single structure regime.