<p>Type&#xa0;1 interferonopathies are rare, mostly inherited disorders of the innate immune system in which uncontrolled type&#xa0;1 interferon production leads to inappropriate inflammatory processes. Based on pathogenetic findings, Janus kinase inhibitors represent a&#xa0;potential targeted treatment option.</p>

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Januskinase-Inhibitoren bei Interferonopathien

  • Andrea Skrabl-Baumgartner,
  • M. Lee-Kirsch

摘要

Type 1 interferonopathies are rare, mostly inherited disorders of the innate immune system in which uncontrolled type 1 interferon production leads to inappropriate inflammatory processes. Based on pathogenetic findings, Janus kinase inhibitors represent a potential targeted treatment option.