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<p>Seronegative spondyloarthropathies comprise a group of heterogenous chronic inflammatory diseases characterized by negative rheumatic factor serology, characteristic clinical patterns, and there is often an association with HLA-B27. Their diversity, often with only subtle or vague symptoms, leads to diagnostic challenges. Early recognition is important to avoid irreversible damage. Advances in imaging and targeted therapy significantly improve prognosis.</p>

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Seronegative Spondyloarthropathien und ihre diagnostischen Herausforderungen

  • 期刊论文

  • 发表日期：

    2026年1月26日

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  • Peter Peichl

摘要

Seronegative spondyloarthropathies comprise a group of heterogenous chronic inflammatory diseases characterized by negative rheumatic factor serology, characteristic clinical patterns, and there is often an association with HLA-B27. Their diversity, often with only subtle or vague symptoms, leads to diagnostic challenges. Early recognition is important to avoid irreversible damage. Advances in imaging and targeted therapy significantly improve prognosis.