Scholarlink

<p>Developing portable, accurate, cost-effective hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) detection platforms is essential for industrial applications and early disease diagnosis. Metal–organic frameworks (MOFs) based composites integrated with metal nanoparticles have been intensively investigated in electrochemical sensing, attributable to their unique architecture and performance characteristics. Herein, PdNPs@NH<sub>2</sub>-MIL-101(Fe) nanocomposites were synthesized via a green reduction process using tannic acid and applied in the development of an enzyme-free electrochemical sensor for H<sub>2</sub>O<sub>2</sub> detection. The synergistic effect of the Pd nanoparticles and the MOFs matrix provided abundant active sites and enhanced electron transfer capability, enabling the sensor to exhibit excellent electrocatalytic performance. Under optimal conditions, the sensing platform exhibited a wide linear response from 10 μM to 15 mM, with a detection threshold of 3.6 μM (S/N = 3). Furthermore, the sensor achieved reliable detection of exogenous H<sub>2</sub>O<sub>2</sub> in commercial mouthwash samples and intracellularly generated H<sub>2</sub>O<sub>2</sub> by cancer cells (HepG2), underscoring its effectiveness in practical scenarios. This work presents a novel strategy for synthesizing high-performance composite nanomaterials and offers valuable insights into the large-scale application of electrochemical sensors for H<sub>2</sub>O<sub>2</sub> detection.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Tannic Acid-Mediated Green Synthesis of Pd@MOFs Nanocomposites for Portable Electrochemical Detection of Hydrogen Peroxide

  • 期刊论文

  • 发表日期：

    2025年10月2日

查看全文
  • Hongmin Gao,
  • Jiahe Deng,
  • Hehua Zhang,
  • Hua Chen,
  • Yang Zhou,
  • Pu Qu,
  • Huan Zhu,
  • Dong Chang,
  • Hongzhi Pan

摘要

Developing portable, accurate, cost-effective hydrogen peroxide (H2O2) detection platforms is essential for industrial applications and early disease diagnosis. Metal–organic frameworks (MOFs) based composites integrated with metal nanoparticles have been intensively investigated in electrochemical sensing, attributable to their unique architecture and performance characteristics. Herein, PdNPs@NH2-MIL-101(Fe) nanocomposites were synthesized via a green reduction process using tannic acid and applied in the development of an enzyme-free electrochemical sensor for H2O2 detection. The synergistic effect of the Pd nanoparticles and the MOFs matrix provided abundant active sites and enhanced electron transfer capability, enabling the sensor to exhibit excellent electrocatalytic performance. Under optimal conditions, the sensing platform exhibited a wide linear response from 10 μM to 15 mM, with a detection threshold of 3.6 μM (S/N = 3). Furthermore, the sensor achieved reliable detection of exogenous H2O2 in commercial mouthwash samples and intracellularly generated H2O2 by cancer cells (HepG2), underscoring its effectiveness in practical scenarios. This work presents a novel strategy for synthesizing high-performance composite nanomaterials and offers valuable insights into the large-scale application of electrochemical sensors for H2O2 detection.

Graphical Abstract