Background <p>Ovarian cancer is the deadliest malignancy of the female reproductive system, in which glycolysis plays a critical role in its progression and treatment. However, no bibliometric review has specifically focused on glycolysis in ovarian cancer metastasis. This study employed bibliometric analysis to map the research landscape and identify emerging trends.</p> Methods <p>Articles on glycolysis and ovarian cancer metastasis were retrieved from the Web of Science Core Collection (data cutoff: November 1, 2025). Trends across countries, institutions, authors, and keywords were analyzed using VOSviewer and CiteSpace, while key pathways and prognostic biomarkers were identified via bioinformatics and survival analyses.</p> Results <p>The United States, China, and Canada are the three countries with the highest research output in the field. <i>Oncotarget</i> ranks first in terms of publication volume of related articles. Although China accounts for nearly half of all publications (<i>n</i> = 352, 49.6%), the citation impact of US and Canadian institutions is more prominent. Fudan University and Shanghai Jiao Tong University are high-output research institutions in this field in China, and the University of Texas MD Anderson Cancer Center demonstrates strong academic influence. Through co-occurrence and co-citation analyses, it can be seen that glycolysis is the core hub linking “tumour microenvironment,” “Cisplatin Resistance,” and “Metabolic Reprogramming” in tandem. The foundational work of Warburg (1956), Vander Heiden et al. (2009), and Hanahan and Weinberg (2011) remains core support for the relevant theoretical framework. Time-dimensional analysis shows that the focus of research has gradually shifted from early phenotypic characterization to mechanistic exploration and drug resistance research, and has recently focused more on targeted therapy and metabolic subtypes. Bibliometric and bioinformatic analyses converge to highlight LDHA, GAPDH, and HK2 as genes that have received substantial research attention, consistent with their established roles in glycolysis. In addition, ADH1B, ALDH1A3, and ADH1C were noted in our screening as showing differential expression and survival associations; these correlative findings do not establish clinical utility but provide a rationale for future functional and prospective validation studies.</p> Conclusions <p>This paper outlines publication trends, national contributions, collaborative networks, and research hotspots regarding glycolysis in ovarian cancer metastasis. The integrated bibliometric and bioinformatic findings offer a structured overview of the research landscape and generate testable hypotheses for future mechanistic and translational investigations.</p>