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Introduction <p>Nomograms are widely recognized as effective predictive tools for estimating cancer prognosis, providing a personalized and practical approach to support clinical decision-making. This study aimed to develop and validate a nomogram for predicting the survival of hospitalized patients with cervical cancer (CC).</p> Methods <p>Eligible data were obtained from the Hospital Information System (SIH) of Brazil’s Unified Health System (SUS) in Mato Grosso State, covering the period from 2011 to 2023. A nomogram was constructed based on a previously published multivariable Cox regression model. Model performance was assessed using Harrell’s concordance index (C-index) and a calibration curve.</p> Results <p>The developed nomogram achieved a C-index of 0.817, indicating good discriminative ability. The most significant predictors included the type of medical procedure performed, the need for ICU admission, and hospital costs. The calibration curve demonstrated good agreement between actual and predicted 30-day survival probabilities.</p> Conclusion <p>A useful clinical nomogram was developed to calculate the probability of survival for hospitalized patients with CC. The model demonstrated excellent performance, assisting healthcare professionals in selecting more appropriate treatments and providing accurate prognostic predictions for both clinical and research contexts.</p>

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Nomogram predicting overall survival in hospitalized cervical cancer patients in Mato Grosso, Brazil

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月11日

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  • Sancho Pedro Xavier,
  • Audêncio Victor,
  • Noemi Dreyer Galvão,
  • Ageo Mario Cândido da Silva

摘要

Introduction

Nomograms are widely recognized as effective predictive tools for estimating cancer prognosis, providing a personalized and practical approach to support clinical decision-making. This study aimed to develop and validate a nomogram for predicting the survival of hospitalized patients with cervical cancer (CC).

Methods

Eligible data were obtained from the Hospital Information System (SIH) of Brazil’s Unified Health System (SUS) in Mato Grosso State, covering the period from 2011 to 2023. A nomogram was constructed based on a previously published multivariable Cox regression model. Model performance was assessed using Harrell’s concordance index (C-index) and a calibration curve.

Results

The developed nomogram achieved a C-index of 0.817, indicating good discriminative ability. The most significant predictors included the type of medical procedure performed, the need for ICU admission, and hospital costs. The calibration curve demonstrated good agreement between actual and predicted 30-day survival probabilities.

Conclusion

A useful clinical nomogram was developed to calculate the probability of survival for hospitalized patients with CC. The model demonstrated excellent performance, assisting healthcare professionals in selecting more appropriate treatments and providing accurate prognostic predictions for both clinical and research contexts.