Scholarlink

<p>Zinc oxide (ZnO) nanoparticle-infused chitosan/PVA-based gels were developed and assessed for potential antibacterial uses. Pure chitosan/PVA gel, chitosan/PVA gel containing 500&#xa0;mg ZnO nanoparticles, and chitosan/PVA gel containing 1 gm ZnO nanoparticles were the three gel compositions that were synthesized. A basic dip-coating technique was also used for coating the gels on cotton fabric in order to show possible material integration. The disc diffusion method was used to evaluate antimicrobial activity against Aspergillus niger, Pseudomonas aeruginosa, Staphylococcus aureus, and Aspergillus flavus. Comparing the ZnO-incorporated gels to the pure chitosan gel, the former showed noticeably better antibacterial activity. Sample C had strain-dependent antimicrobial behavior, whereas Sample B demonstrated the strongest antibacterial activity among the formulations, with zones of inhibition of 35&#xa0;mm against S. aureus and 27&#xa0;mm against P. aeruginosa. Analysis using Field Emission Scanning Electron Microscopy (FE-SEM) verified that ZnO nanoparticles were present and evenly distributed throughout the gel matrix. These findings emphasize the potential of chitosan/PVA gels as antimicrobial coating materials by showing how ZnO addition successfully improves their antibacterial efficacy.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effect of ZnO Nanoparticles on the Antimicrobial Activity of Chitosan/PVA-Based Gels

  • 期刊论文

  • 发表日期：

    2026年4月16日

查看全文
  • Anju Singhwane,
  • Anita Tilwari,
  • Sarika Verma,
  • Ashish K. Sarangi,
  • Sanjibani Mishra,
  • Ranjan K. Mohapatra

摘要

Zinc oxide (ZnO) nanoparticle-infused chitosan/PVA-based gels were developed and assessed for potential antibacterial uses. Pure chitosan/PVA gel, chitosan/PVA gel containing 500 mg ZnO nanoparticles, and chitosan/PVA gel containing 1 gm ZnO nanoparticles were the three gel compositions that were synthesized. A basic dip-coating technique was also used for coating the gels on cotton fabric in order to show possible material integration. The disc diffusion method was used to evaluate antimicrobial activity against Aspergillus niger, Pseudomonas aeruginosa, Staphylococcus aureus, and Aspergillus flavus. Comparing the ZnO-incorporated gels to the pure chitosan gel, the former showed noticeably better antibacterial activity. Sample C had strain-dependent antimicrobial behavior, whereas Sample B demonstrated the strongest antibacterial activity among the formulations, with zones of inhibition of 35 mm against S. aureus and 27 mm against P. aeruginosa. Analysis using Field Emission Scanning Electron Microscopy (FE-SEM) verified that ZnO nanoparticles were present and evenly distributed throughout the gel matrix. These findings emphasize the potential of chitosan/PVA gels as antimicrobial coating materials by showing how ZnO addition successfully improves their antibacterial efficacy.

Graphical Abstract