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<p>Turmeric, a bright yellow spice from India, belongs to the Curcuma family<i>.</i> The phytochemical compounds curcumin, demethoxycurcumin and bisdemethoxycurcumin (curcuminoids) in turmeric are traditionally used as an antimicrobial agent and also as a growth enhancer in both livestock and poultry. Among these phytocompounds in turmeric, the lipophilic polyphenol compound, curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione), has unique properties such as anti-bacterial, anti-inflammatory, anti-oxidant, and anti-cancer effects. However, curcumin also has low water solubility, bioavailability and pharmacokinetic properties for therapeutic applications. To overcome these drawbacks, a variety of curcumin formulations have been established. Recently, nanotechnology emerged as vibrant subject to address variety of issues including enhancing the bioavailability. The synthesized nanocurcumin could be employed as an animal feed additive to improve the reproductive health, egg and meat quality, gut health and growth promotion. The synthesized nanocurcumin can be analyzed by various analytical techniques such as UV–Visible spectroscopy, FTIR and HPLC analysis. In addition, different extraction methods are involved; its formulations, identification and characterization are essential for its application in the animal feed and for enhanced biological activities.</p>

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Curcuminoids: Extraction, Characterization, and Nanoformulations for Enhanced Applications and Therapeutic Outcomes

  • 期刊论文

  • 发表日期：

    2025年10月28日

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  • Duraisamy Rajendran,
  • Sriramulu Mohana,
  • Muniswamy Shobha,
  • Sellappan Selvaraju,
  • Artabandhu Sahoo,
  • Marappan Gopi

摘要

Turmeric, a bright yellow spice from India, belongs to the Curcuma family. The phytochemical compounds curcumin, demethoxycurcumin and bisdemethoxycurcumin (curcuminoids) in turmeric are traditionally used as an antimicrobial agent and also as a growth enhancer in both livestock and poultry. Among these phytocompounds in turmeric, the lipophilic polyphenol compound, curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione), has unique properties such as anti-bacterial, anti-inflammatory, anti-oxidant, and anti-cancer effects. However, curcumin also has low water solubility, bioavailability and pharmacokinetic properties for therapeutic applications. To overcome these drawbacks, a variety of curcumin formulations have been established. Recently, nanotechnology emerged as vibrant subject to address variety of issues including enhancing the bioavailability. The synthesized nanocurcumin could be employed as an animal feed additive to improve the reproductive health, egg and meat quality, gut health and growth promotion. The synthesized nanocurcumin can be analyzed by various analytical techniques such as UV–Visible spectroscopy, FTIR and HPLC analysis. In addition, different extraction methods are involved; its formulations, identification and characterization are essential for its application in the animal feed and for enhanced biological activities.